10rx vs PrescrYbe
An in-depth comparison of two leading GLP-1 Providers
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PrescrYbe
Best for: shoppers who want an oral GLP-1 option or a low-dose microdosing tier
Visit PrescrYbe →10rx and PrescrYbe are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $96.67/mo versus $179/mo, and PrescrYbe edges ahead overall (7.3 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
10rx
PrescrYbe
Card reads "$249 per 4 week". A 4-week cycle is 13 charges a year, not 12 — the site states the cadence openly.
Card reads "$339 per 4 week".
Card reads "$279 per 4 week" for the oral formulation.
Low-dose tier, "$179 per 4 week".
Low-dose tier, "$179 per 4 week".
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What’s included
10rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
PrescrYbe
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
10rx
7.1/10
PrescrYbe
7.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 10rx | PrescrYbe |
|---|---|---|
| Starting Price | ✓$96.67/mo | $179/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 10rx
10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.
Read our full 10rx review →About PrescrYbe
PrescrYbe is a cash-pay telehealth platform offering compounded semaglutide and tirzepatide as injections or an oral formulation, plus low-dose microdosing tiers from $179. Pricing is billed every 4 weeks rather than monthly and the cadence is stated on the product card. Consultations, medication and shipping are bundled into one price, and you are not charged if a provider finds you ineligible.
Read our full PrescrYbe review →Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to pin down
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
PrescrYbe
What we like
- Five GLP-1 tiers including an oral semaglutide option and $179 microdosing for both drugs
- Billing cadence is printed on the product card — most sites hide the 4-week cycle
- Price shown before you start intake, not after
- Consultation, medication and shipping bundled into one cash-pay price
- Full refund if a provider finds you ineligible: "If you don't qualify, you don't pay"
Watch-outs
- Charged every 4 weeks, so a year costs 13 payments, not 12 — $3,237/yr on semaglutide, not $2,988
- Neither the prescribing medical group nor the pharmacy partner is named anywhere in the terms
- No published state list — terms say only that some services may not be available in all states
- Cancellation is by email to care@prescrybe.health; no self-serve cancel is documented
- No support phone number published
- Compounded only, and the terms confirm compounded drugs are not FDA approved
Our Verdict
PrescrYbe edges out 10rx with a higher overall score of 7.3/10 and is particularly strong for shoppers who want an oral GLP-1 option or a low-dose microdosing tier. 10rx remains a solid alternative, especially if you're looking for low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.
Choose 10rx if…
You want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $96.67/mo.
Choose PrescrYbe if…
You want shoppers who want an oral GLP-1 option or a low-dose microdosing tier and a starting price around $179/mo.
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Get started →10rx vs PrescrYbe: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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