Always verify pricing and state availability on the provider's website before signing up.How our reviews work →

10rx vs Next Vial

An in-depth comparison of two leading GLP-1 Providers

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

10rx logo

10rx

7.0
★★★3.5

Best for: budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons

Visit 10rx
VS
Next Vial logo

Next Vial

7.1
★★★3.6

Best for: people seeking compounded GLP-1 care with LegitScript certification and a named pharmacy partner

Visit Next Vial

10rx and Next Vial are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $99.67/mo versus $249.97/mo, and Next Vial edges ahead overall (7.1 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

10rx

Injectablecompounded injection
$99.67/mo
semaglutide

Compounded; GLP-1 options as low as under $100/mo

Injectablecompounded injection
$149.67/mo
tirzepatide

Compounded GLP-1 + GIP

Next Vial

StandardCompounded
$249.97/mo
semaglutide

Starting monthly rate for GLP-1 program; tirzepatide rate not published.

What’s included

10rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Next Vial

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

7.0/10

Overall

Next Vial

7.1/10

Value25%

8.5A
vs
B
6.0

Effectiveness25%

7.0A
vs
B
7.0

User Experience15%

7.0A
vs
B
7.5

Trust & Safety15%

5.0A
vs
B
8.0

Accessibility10%

7.5A
vs
B
8.0

Support10%

6.0A
vs
B
7.0

Features & Coverage

Feature10rxNext Vial
Starting Price$99.67/mo$249.97/mo
Features8 features7 features
States AvailableNot disclosed49
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 10rx

10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.

Read our full 10rx review →

About Next Vial

Fully online GLP-1 telehealth marketplace connecting patients with licensed providers for compounded semaglutide and tirzepatide injections, including microdose options. LegitScript verified with medication dispensed through Manifest Pharmacy (Greer, SC). No membership required — one transparent price covering consultation, medication, and free shipping. Serves 49 states.

Read our full Next Vial review →

Pros & Cons

10rx

What we like

  • Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
  • Free online health quiz with board-certified telehealth doctors reviewing eligibility
  • Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
  • Says it ships to all 50 states with discreet delivery from licensed pharmacy partners

Watch-outs

  • Doesn't publish its legal operating entity, so accountability is hard to verify
  • Pharmacy partners are described as licensed but none are named
  • No terms-of-service page is posted, and FAQ answers load only via script
  • Compounded semaglutide and tirzepatide only — no brand-name or oral options
  • No LegitScript or third-party accreditation is shown on the site

Next Vial

What we like

  • LegitScript verified with named pharmacy partner (Manifest Pharmacy, Greer, SC)
  • No membership fees — one all-in price covering consultation, medication, and shipping
  • Compounded semaglutide, tirzepatide, and microdose options available
  • Free rushed shipping; serves 49 states nationwide
  • Board-certified physician oversight with ongoing provider support

Watch-outs

  • Tirzepatide pricing not listed publicly (starting price covers GLP-1 generally)
  • Compounded medications are not FDA-approved
  • Labs and nutritional coaching not disclosed
  • Microdose pricing not published on product page
  • Alaska not listed among served states

Our Verdict

Winner: Next Vial

Next Vial edges out 10rx with a higher overall score of 7.1/10 and is particularly strong for people seeking compounded GLP-1 care with LegitScript certification and a named pharmacy partner. 10rx remains a solid alternative, especially if you're looking for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.

Choose 10rx if…

You want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.

Choose Next Vial if…

You want people seeking compounded GLP-1 care with LegitScript certification and a named pharmacy partner and a starting price around $249.97/mo.

Ready to start? Vetted GLP-1 providers

Vetted telehealth providers that prescribe GLP-1 online, ranked by our editorial score.

No insurance needed · vetted by our editors

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

7.9

Live Vital

Shoppers who want low-cost, physician-led compounded GLP-1 with peptide and hormone options

7.9

Bodybuilding Health+

Fitness-brand compounded GLP-1 with hormone and performance programs

7.8

Gala

Compounded GLP-1/GIP combo therapy on a yearly subscription with free shipping nationwide

10rx vs Next Vial: FAQ

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Related comparisons

Continue exploring 10rx and Next Vial head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.