10rx vs Medi-Weightloss
An in-depth comparison of two leading GLP-1 Providers
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10rx
Best for: budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons
Visit 10rx →
Medi-Weightloss
Best for: Patients wanting in-person physician-supervised GLP-1 care with insurance/HSA use
Visit Medi-Weightloss →10rx and Medi-Weightloss are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $99.67/mo versus $199/mo, and Medi-Weightloss edges ahead overall (7.3 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
10rx
Compounded; GLP-1 options as low as under $100/mo
Compounded GLP-1 + GIP
Medi-Weightloss
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What’s included
10rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Medi-Weightloss
Inclusions not disclosed.
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
10rx
7.1/10
Medi-Weightloss
7.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 10rx | Medi-Weightloss |
|---|---|---|
| Starting Price | ✓$99.67/mo | $199/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About 10rx
10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.
Read our full 10rx review →About Medi-Weightloss
Medi-Weightloss is an established physician-supervised weight-loss brand with 130-plus locations nationwide plus telehealth. Its GLP-1 program prescribes branded Wegovy and Zepbound as well as compounded semaglutide and compounded tirzepatide, alongside older agents like phentermine. Programs are evidence-based, with body-composition analysis and personalized plans. A new-patient visit runs about $199 and includes a medical assessment, labs and GLP-1 eligibility review; ongoing medication costs depend on the plan. Insurance is accepted at many locations and HSA/FSA accounts are welcome.
Read our full Medi-Weightloss review →Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to verify
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
Medi-Weightloss
What we like
- Both branded (Wegovy, Zepbound) and compounded semaglutide/tirzepatide
- Established brand with 130+ physician-supervised locations nationwide
- Telehealth plus in-person clinic options
- Accepts insurance at many locations; HSA/FSA welcome
- Includes body-composition analysis and personalized plans
Watch-outs
- Ongoing medication pricing not transparently posted; varies by plan
- $199 new-patient visit fee before medication costs
- Frequent (often weekly) visits expected for some patients
- Compounded products are not FDA-approved or evaluated
Our Verdict
Medi-Weightloss edges out 10rx with a higher overall score of 7.3/10 and is particularly strong for Patients wanting in-person physician-supervised GLP-1 care with insurance/HSA use. 10rx remains a solid alternative, especially if you're looking for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.
Choose 10rx if…
You want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.
Choose Medi-Weightloss if…
You want Patients wanting in-person physician-supervised GLP-1 care with insurance/HSA use and a starting price around $199/mo.
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Found
Mainstream telehealth GLP-1 access
From $99/mo
Get started →Breeze Meds
Compounded GLP-1 access with named prescribers and 4-pharmacy network
From $169/mo
Get started →GobyMeds
Budget-conscious shoppers
From $93/mo
Get started →10rx vs Medi-Weightloss: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.