10rx vs Lyfe Rx
An in-depth comparison of two leading GLP-1 Providers
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10rx
Best for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-onsStarting at $99.67/mo
Lyfe Rx
Best for use with caution — FDA warning letter on fileStarting at $225/mo
Side-by-Side Comparison
| Feature | 10rx | Lyfe Rx |
|---|---|---|
| Overall Score | 7.0/10 | 7.0/10 |
| Starting Price | ✓$99.67/mo | $225/mo |
| Editorial Rating | 3.5 ★ /5 | 3.5 ★ /5 |
| Features | ✓8 features | 3 features |
| States Available | 0 | 0 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | ✓None | 1 warning |
Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to verify
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
Lyfe Rx
What we like
- Both compounded semaglutide and tirzepatide available
- Delivery to all 50 states with 1–3 day pharmacy turnaround
Watch-outs
- FDA warning letter (09/2025) for misbranding compounded GLP-1 products
- No visible LegitScript or PCAB accreditation
- Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
- Shopify-based e-commerce storefront — less clinical infrastructure
Our Verdict
Both 10rx and Lyfe Rx score equally well overall — the right choice depends on your priorities. Choose 10rx if you want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons, or Lyfe Rx if use with caution — FDA warning letter on file matters most to you.
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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