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10rx vs Lean Rx

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
10rx logo

10rx

7.1
★★★3.6/5

Best for: budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons

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VS
Lean Rx logo

Lean Rx

6.8
★★★☆☆3.4/5

Best for: Patients wanting compounded GLP-1 in injectable, sublingual, or tablet form

Visit Lean Rx

10rx and Lean Rx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $99.67/mo versus $266/mo, and 10rx edges ahead overall (7.1 vs 6.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

10rx

Injectablecompounded injection
$99.67/mo
semaglutide

Compounded; GLP-1 options as low as under $100/mo

Injectablecompounded injection
$149.67/mo
tirzepatide

Compounded GLP-1 + GIP

Lean Rx

StartingCompounded
$266/mo
semaglutide
StartingCompounded
$399/mo
tirzepatide

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What’s included

10rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Lean Rx

What the monthly price covers

Medication

Included

Provider visits

Not disclosed

Shipping

Not disclosed

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

7.1/10

Overall

Lean Rx

6.8/10

Value25%

8.5A
vs
B
7.0

Effectiveness25%

7.0A
vs
B
7.0

User Experience15%

7.0A
vs
B
6.5

Trust & Safety15%

5.3A
vs
B
6.8

Accessibility10%

7.5A
vs
B
6.5

Support10%

6.4A
vs
B
6.5

Features & Coverage

Feature10rxLean Rx
Starting Price$99.67/mo$266/mo
Features8 features8 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 10rx

10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.

Read our full 10rx review →

About Lean Rx

Lean Rx is a Sacramento-based telehealth technology platform offering compounded GLP-1 weight loss medications. Patients complete an online medical history and a telehealth call with an independent licensed provider, who prescribes when appropriate, then receive medication shipped home. Lean Rx offers compounded semaglutide from $266 per month and tirzepatide from $399 per month, in injectable, sublingual, and tablet forms. It advertises upfront pricing with no hidden fees, and notes it is a technology platform, not a healthcare provider. No state list is published.

Read our full Lean Rx review →

Pros & Cons

10rx

What we like

  • Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
  • Free online health quiz with board-certified telehealth doctors reviewing eligibility
  • Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
  • Says it ships to all 50 states with discreet delivery from licensed pharmacy partners

Watch-outs

  • Doesn't publish its legal operating entity, so accountability is hard to verify
  • Pharmacy partners are described as licensed but none are named
  • No terms-of-service page is posted, and FAQ answers load only via script
  • Compounded semaglutide and tirzepatide only — no brand-name or oral options
  • No LegitScript or third-party accreditation is shown on the site

Lean Rx

What we like

  • Both semaglutide and tirzepatide offered
  • Three formulations: injectable, sublingual, and tablet
  • Upfront pricing with no hidden fees advertised
  • Semaglutide starts at a low $266/month
  • Telehealth call with a licensed provider before prescribing

Watch-outs

  • Compounded-only; no FDA-approved branded options
  • No published state availability list
  • Platform is technology only, not a healthcare provider itself
  • Provider credentials not detailed on site

Our Verdict

Winner: 10rx

10rx edges out Lean Rx with a higher overall score of 7.1/10 and is particularly strong for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons. Lean Rx remains a solid alternative, especially if you're looking for Patients wanting compounded GLP-1 in injectable, sublingual, or tablet form.

Choose 10rx if…

You want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.

Choose Lean Rx if…

You want Patients wanting compounded GLP-1 in injectable, sublingual, or tablet form and a starting price around $266/mo.

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7.6

Maximus

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8.0

Sesame Care

Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding

6.9

Try Ageless

Lowest-tier compounded GLP-1 in injection, troche and sublingual forms

10rx vs Lean Rx: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.