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10rx vs Helix Wellness Rx

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
10rx logo

10rx

7.1
★★★★☆3.6/5

Best for: low-cost compounded GLP-1 with NAD+ and sermorelin add-ons

Visit 10rx →
VS

Helix Wellness Rx

6.3
★★★☆☆3.2/5

Best for: self-serve cancellation and a low-dose GLP-1 entry point

Visit Helix Wellness Rx →

10rx and Helix Wellness Rx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $96.67/mo versus $149/mo, and 10rx edges ahead overall (7.1 vs 6.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

10rx

Injectablecompounded injection
$96.67/mo
semaglutide
Injectablecompounded injection
$149.67/mo
tirzepatide

Helix Wellness Rx

Program floor; per-drug price not publishedCompounded
$149/mo
semaglutide

$149/mo is the advertised floor across all GLP-1 and peptide programs, not a semaglutide price. The site states "Plans from $149/mo · confirmed after provider review" and the semaglutide, tirzepatide and microdose pages publish no price at all.

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What’s included

10rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Helix Wellness Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

7.1/10

Overall

Helix Wellness Rx

6.3/10

Value25%

8.5A
vs
B
6.0

Effectiveness25%

7.0A
vs
B
7.5

User Experience15%

7.0A
vs
B
5.5

Trust & Safety15%

5.3A
vs
B
5.0

Accessibility10%

7.5A
vs
B
7.0

Support10%

6.4A
vs
B
6.0

Features & Coverage

Feature10rxHelix Wellness Rx
Starting Price✓$96.67/mo$149/mo
Features✓8 features6 features
States AvailableNot disclosedNot disclosed
Compounded—✓ Yes
Brand Name——
FSA/HSA Accepted——
FDA WarningsNoneNone

About 10rx

10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.

Read our full 10rx review →

About Helix Wellness Rx

Helix Wellness Rx offers physician-guided semaglutide, tirzepatide and a low-dose GLP-1 microdose alongside a long list of peptide and hormone programs. Programs are advertised from $149/mo, but no per-drug price is published anywhere — the site states cost is "confirmed after provider review". Cancellation is self-serve from the user portal up to 48 hours before the billing date.

Read our full Helix Wellness Rx review →

Pros & Cons

10rx

What we like

  • Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
  • Free online health quiz with board-certified telehealth doctors reviewing eligibility
  • Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
  • Says it ships to all 50 states with discreet delivery from licensed pharmacy partners

Watch-outs

  • Doesn't publish its legal operating entity, so accountability is hard to pin down
  • Pharmacy partners are described as licensed but none are named
  • No terms-of-service page is posted, and FAQ answers load only via script
  • Compounded semaglutide and tirzepatide only — no brand-name or oral options
  • No LegitScript or third-party accreditation is shown on the site

Helix Wellness Rx

What we like

  • Self-serve cancellation from the user portal, up to 48 hours before the billing date
  • Three GLP-1 routes including a low-dose microdose entry point
  • Free 2-3 day shipping and no insurance required
  • Pre-screening opens with a goals question rather than a request for contact details
  • Publishes a toll-free support line

Watch-outs

  • No per-drug price is published — semaglutide, tirzepatide and microdose pages all show no cost at all
  • The only figure given is a $149/mo floor spanning GLP-1s and peptides, "confirmed after provider review"
  • The privacy page publishes a placeholder phone number, (555) 000-0000
  • Pharmacy and medical groups are named as third-party beneficiaries in the terms but never identified
  • No state list is published
  • Advertises peptides whose regulatory status shifted in 2026 — check what is actually available before ordering one

Our Verdict

Winner: 10rx

10rx edges out Helix Wellness Rx with a higher overall score of 7.1/10 and is particularly strong for low-cost compounded GLP-1 with NAD+ and sermorelin add-ons. Helix Wellness Rx remains a solid alternative, especially if you're looking for self-serve cancellation and a low-dose GLP-1 entry point.

Choose 10rx if…

You want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $96.67/mo.

Choose Helix Wellness Rx if…

You want self-serve cancellation and a low-dose GLP-1 entry point and a starting price around $149/mo.

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7.7

TrimRx

Best overall value

7.6

Sprout Health

LegitScript-certified compounded GLP-1 via named pharmacies

7.8

Care Bare Rx

LGBTQ+-inclusive compounded GLP-1 telehealth

10rx vs Helix Wellness Rx: FAQ

10rx is cheaper. Its lowest ongoing monthly cash price is $96.67/mo, compared with $149/mo for Helix Wellness Rx. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
10rx scores higher overall at 7.1/10 versus 6.3/10, and is particularly strong for low-cost compounded GLP-1 with NAD+ and sermorelin add-ons. That said, Helix Wellness Rx is a better fit if you want self-serve cancellation and a low-dose GLP-1 entry point.
Neither 10rx nor Helix Wellness Rx publicly lists its exact state availability. Most national GLP-1 telehealth providers operate in the majority of states — confirm your state is covered during sign-up.
Neither 10rx nor Helix Wellness Rx is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, 10rx is cheaper at $96.67/mo versus $149/mo at Helix Wellness Rx.

Key terms, explained

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Continue exploring 10rx and Helix Wellness Rx head-to-heads in the same category.

Or see the full category ranking.

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