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10rx vs Genesis Lifestyle Medicine

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
10rx logo

10rx

7.1
★★★3.6/5

Best for: budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons

Visit 10rx
VS
Genesis Lifestyle Medicine logo

Genesis Lifestyle Medicine

6.6
★★★☆☆3.3/5

Best for: hybrid med-spa GLP-1 with 18 clinics and brand-name access

Visit Genesis Lifestyle Medicine

10rx and Genesis Lifestyle Medicine are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts at $99.67/mo, and 10rx edges ahead overall (7.1 vs 6.6 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

10rx

Injectablecompounded injection
$99.67/mo
semaglutide

Compounded; GLP-1 options as low as under $100/mo

Injectablecompounded injection
$149.67/mo
tirzepatide

Compounded GLP-1 + GIP

Genesis Lifestyle Medicine

Pricing not publicly listed.

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What’s included

10rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Genesis Lifestyle Medicine

Inclusions not disclosed.

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

7.1/10

Overall

Genesis Lifestyle Medicine

6.6/10

Value25%

8.5A
vs
B
6.0

Effectiveness25%

7.0A
vs
B
7.0

User Experience15%

7.0A
vs
B
7.0

Trust & Safety15%

5.3A
vs
B
7.0

Accessibility10%

7.5A
vs
B
5.0

Support10%

6.4A
vs
B
7.0

Features & Coverage

Feature10rxGenesis Lifestyle Medicine
Starting Price$99.67/mo
Features8 features8 features
States AvailableNot disclosed8
Compounded
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 10rx

10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.

Read our full 10rx review →

About Genesis Lifestyle Medicine

Genesis Lifestyle Medicine is a hybrid in-office and telehealth medical spa with 18 clinic locations across 8 states, offering brick-and-mortar accountability uncommon among DTC GLP-1 providers. It spans weight loss, hormone therapy, aesthetics, and hair restoration. For weight loss it offers both compounded semaglutide and tirzepatide and brand-name Wegovy and Zepbound, so patients who prefer FDA-approved options needn't switch platforms.

Read our full Genesis Lifestyle Medicine review →

Pros & Cons

10rx

What we like

  • Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
  • Free online health quiz with board-certified telehealth doctors reviewing eligibility
  • Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
  • Says it ships to all 50 states with discreet delivery from licensed pharmacy partners

Watch-outs

  • Doesn't publish its legal operating entity, so accountability is hard to verify
  • Pharmacy partners are described as licensed but none are named
  • No terms-of-service page is posted, and FAQ answers load only via script
  • Compounded semaglutide and tirzepatide only — no brand-name or oral options
  • No LegitScript or third-party accreditation is shown on the site

Genesis Lifestyle Medicine

What we like

  • 18 physical clinics allow in-person consults and injections across 8 states
  • Dual modality — compounded sema/tirz plus brand-name Wegovy and Zepbound on one platform
  • Med spa model lets patients combine weight loss, hormone therapy, and aesthetics
  • Established brand with an 18-location footprint and patient testimonials
  • Telehealth available for remote patients in served states
  • LegitScript verified

Watch-outs

  • Pricing not disclosed publicly — gated behind the consultation flow
  • Specific 503A/503B pharmacy partner not named, and the designation not specified
  • No FDA compounded-medication disclaimer visible on the homepage
  • Named medical director not formally disclosed (only a 'Dr. Spinoso' testimonial)
  • Corporate legal entity and governing law not disclosed
  • Only 8 states served — much narrower than national competitors
  • Telehealth runs on a separate domain, fragmenting the brand trail

Our Verdict

Winner: 10rx

10rx edges out Genesis Lifestyle Medicine with a higher overall score of 7.1/10 and is particularly strong for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons. Genesis Lifestyle Medicine remains a solid alternative, especially if you're looking for hybrid med-spa GLP-1 with 18 clinics and brand-name access.

Choose 10rx if…

You want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.

Choose Genesis Lifestyle Medicine if…

You want hybrid med-spa GLP-1 with 18 clinics and brand-name access.

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7.6

Maximus

Men seeking compounded GLP-1 alongside testosterone optimization

8.0

Sesame Care

Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding

6.9

Try Ageless

Lowest-tier compounded GLP-1 in injection, troche and sublingual forms

10rx vs Genesis Lifestyle Medicine: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.