10rx vs Edessa
An in-depth comparison of two leading GLP-1 Providers
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Edessa
Best for: cheap month-to-month compounded GLP-1 with tirzepatide and an oral tablet option
Visit Edessa →10rx and Edessa are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $96.67/mo versus $179/mo, and Edessa edges ahead overall (7.3 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
10rx
Edessa
Plan table on myedessa.com/product-glp-1-injection.html, verified 2026-09-01: 1 month $179, 3 month $160/mo, 6 month $135/mo. The homepage's 'Start for just $135' is the six-month prepay rate, not the month-to-month price.
1 month $229, 3 month $209/mo, 6 month $199/mo (myedessa.com/product-glp-1-tablet.html). 'Compounded semaglutide medication' is what the page says you receive.
1 month $239, 3 month $219/mo, 6 month $209/mo (myedessa.com/product-glp-1-tirzepatide.html).
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What’s included
10rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Edessa
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
10rx
7.1/10
Edessa
7.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 10rx | Edessa |
|---|---|---|
| Starting Price | ✓$96.67/mo | $179/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | 51 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About 10rx
10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.
Read our full 10rx review →About Edessa
Edessa is a Las Vegas-based telehealth brand selling compounded semaglutide injections at $179/mo month-to-month (down to $135/mo on a six-month plan), a daily dissolvable semaglutide tablet from $229/mo and compounded tirzepatide from $239/mo. Care is delivered by OpenLoop Health clinicians and four named US compounding pharmacies, with medication, consult and expedited shipping in one cash-pay price and the same price at every dose.
Read our full Edessa review →Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to verify
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
Edessa
What we like
- Month-to-month compounded semaglutide at $179 with no contract, dropping to $135/mo on the six-month plan
- Tirzepatide and a daily dissolvable tablet sit alongside the standard weekly injection
- Every product page prints the 1-, 3- and 6-month rate side by side and states 'Same price, every dose'
- Medication, physician review, ongoing check-ins and free expedited cold-chain shipping are in the one price
- Four named US pharmacy partners with addresses (RedRock, Health Warehouse, Precision Compounding, Triad Rx)
- Care delivered through the OpenLoop Health licensed provider network, listed in all 50 states and DC
- Cash-pay with no insurance required, and HSA/FSA eligible
Watch-outs
- The advertised '$135' is the six-month prepay rate; month-to-month is $179, and the FAQ still calls $135 a first-month price 'with no contract'
- The 'no questions asked' guarantee is not the policy: the Terms need proof of no weight loss after five months, minus 25% consult fees
- The Terms also say all sales are final and consult fees are never refundable
- The Terms contain no auto-renewal or cancellation section, so what happens at the end of a prepaid term is not published
- You pay before the clinician review — an OpenLoop clinician meets you after checkout to decide whether you qualify
- Homepage figures (100,000+ patients, 18% average weight loss, 93% kept it off) carry no cited source
- No published support hours, and support is email and phone only
- Compounded GLP-1s are not FDA-approved
Our Verdict
Edessa edges out 10rx with a higher overall score of 7.3/10 and is particularly strong for cheap month-to-month compounded GLP-1 with tirzepatide and an oral tablet option. 10rx remains a solid alternative, especially if you're looking for low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.
Choose 10rx if…
You want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $96.67/mo.
Choose Edessa if…
You want cheap month-to-month compounded GLP-1 with tirzepatide and an oral tablet option and a starting price around $179/mo.
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Listed for disclosure only — see its FDA warning and BBB complaints first
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Get started →10rx vs Edessa: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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