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10rx vs CLYR Health

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
10rx logo

10rx

7.1
★★★3.6/5

Best for: budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons

Visit 10rx
VS
CLYR Health logo

CLYR Health

7.7
★★★3.9/5

Best for: Flat-rate compounded GLP-1 with pricing that does not increase as your dose goes up

Visit CLYR Health

10rx and CLYR Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $99.67/mo versus $229/mo, and CLYR Health edges ahead overall (7.7 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

10rx

Injectablecompounded injection
$99.67/mo
semaglutide

Compounded; GLP-1 options as low as under $100/mo

Injectablecompounded injection
$149.67/mo
tirzepatide

Compounded GLP-1 + GIP

CLYR Health

Compounded semaglutide + B12Compounded
$229/mo
semaglutide

Flat any-dose $229/mo; 3-month prepay $189/mo ($567 billed once)

Compounded tirzepatide + B12Compounded
$249/mo
tirzepatide

$249/mo standard dose (up to 3mL); 3-month prepay $199/mo; higher dose 4-8mL $349/mo

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What’s included

10rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

CLYR Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Not disclosed

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

7.1/10

Overall

CLYR Health

7.7/10

Value25%

8.5A
vs
B
7.5

Effectiveness25%

7.0A
vs
B
8.0

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

5.3A
vs
B
8.0

Accessibility10%

7.5A
vs
B
7.0

Support10%

6.4A
vs
B
7.0

Features & Coverage

Feature10rxCLYR Health
Starting Price$99.67/mo$229/mo
Features8 features6 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 10rx

10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.

Read our full 10rx review →

About CLYR Health

CLYR Health is a Florida-based telehealth pharmacy offering compounded GLP-1 weight-loss injections alongside sexual-health, longevity and wellness treatments. It sells compounded semaglutide + B12 from $229/mo and compounded tirzepatide + B12 from $249/mo on flat 'any dose, one price' billing, with 3-month prepay plans that lower the effective rate. Brand Zepbound and oral GLP-1 options are also listed. LegitScript Certified and fulfilled by a named 503A pharmacy.

Read our full CLYR Health review →

Pros & Cons

10rx

What we like

  • Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
  • Free online health quiz with board-certified telehealth doctors reviewing eligibility
  • Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
  • Says it ships to all 50 states with discreet delivery from licensed pharmacy partners

Watch-outs

  • Doesn't publish its legal operating entity, so accountability is hard to verify
  • Pharmacy partners are described as licensed but none are named
  • No terms-of-service page is posted, and FAQ answers load only via script
  • Compounded semaglutide and tirzepatide only — no brand-name or oral options
  • No LegitScript or third-party accreditation is shown on the site

CLYR Health

What we like

  • Flat 'any dose, one price' billing so the monthly cost does not rise as your dose climbs
  • LegitScript Certified with a named 503A pharmacy partner (The Pharmacy Hub, Miami FL) and MD Integrations clinicians
  • 3-month prepay drops semaglutide to $189/mo and tirzepatide to $199/mo

Watch-outs

  • State availability gated behind intake; not published on the marketing site
  • Standing monthly rates ($229-249) run above the cheapest compounded competitors
  • Broad catalog (weight loss, sexual health, longevity) rather than a weight-loss specialist

Our Verdict

Winner: CLYR Health

CLYR Health edges out 10rx with a higher overall score of 7.7/10 and is particularly strong for Flat-rate compounded GLP-1 with pricing that does not increase as your dose goes up. 10rx remains a solid alternative, especially if you're looking for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.

Choose 10rx if…

You want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.

Choose CLYR Health if…

You want Flat-rate compounded GLP-1 with pricing that does not increase as your dose goes up and a starting price around $229/mo.

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6.9

TMates

Nationwide compounded GLP-1 availability including Puerto Rico

7.9

Trimi Health

Budget-conscious shoppers

8.0

ShedRx

Mainstream telehealth GLP-1 access

10rx vs CLYR Health: FAQ

Key terms, explained

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.