10rx vs Brightmeds
An in-depth comparison of two leading GLP-1 Providers
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10rx
Best for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-onsStarting at $99.67/mo
Brightmeds
Best for compounded or brand GLP-1 bundled with TRT and peptides for menStarting at $325/mo
Side-by-Side Comparison
| Feature | 10rx | Brightmeds |
|---|---|---|
| Overall Score | ✓7.0/10 | 6.9/10 |
| Starting Price | ✓$99.67/mo | $325/mo |
| Editorial Rating | 3.5 ★ /5 | 3.5 ★ /5 |
| Features | 8 features | 8 features |
| States Available | 0 | ✓47 |
| Compounded | — | — |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to verify
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
Brightmeds
What we like
- One login covers GLP-1, TRT, peptides, and longevity — convenient for men exploring weight loss and hormones
- Offers both compounded GLP-1s and brand-name FDA-approved Zepbound (pens and vials)
- Microdosing protocols available for compounded semaglutide and tirzepatide
- Publishes the FDA compounded-medication disclaimer with explicit 503A and 503B facility mention
- Dispensing pharmacies named in Terms (Beaker Pharmacy and Red Rock Pharmacy)
- Free baseline labs for TRT clients, and a money-back guarantee if not approved
- 47-state footprint (excludes AL, AR, MS) — broader than most TRT-focused platforms
- Tirzepatide is flat-priced across all doses ($289 first month, then $397/mo thereafter) — no extra cost as you titrate up
Watch-outs
- Pricing isn't itemized on the main pages — you must click through to landers or the application flow
- Brand-name Zepbound carries a separate $100 doctor consult fee on top of drug cost
- No LegitScript certification mentioned on the site
- Named medical director not disclosed
- Trustpilot rating not independently audited
- Multi-vertical bundling can distract patients who only want GLP-1
- $333/mo ongoing compounded semaglutide is mid-to-high; cheaper options start at $149–$249/mo
- $189 first-month promo is a loss-leader — true ongoing cost is $333/mo (sema) or $397/mo (tirz)
Our Verdict
10rx edges out Brightmeds with a higher overall score of 7.0/10 and is particularly strong for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons. Brightmeds remains a solid alternative, especially if you're looking for compounded or brand GLP-1 bundled with TRT and peptides for men.
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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