10rx vs Brightmeds
An in-depth comparison of two leading GLP-1 Providers
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10rx
Best for: budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons
Visit 10rx →Brightmeds
Best for: compounded or brand GLP-1 bundled with TRT and peptides for men
Visit Brightmeds →10rx and Brightmeds are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $99.67/mo versus $100/mo, and Brightmeds edges ahead overall (7.4 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
10rx
Compounded; GLP-1 options as low as under $100/mo
Compounded GLP-1 + GIP
Brightmeds
'Starting at $189' is the only published sema price (1-month plan per on-page comparison chart); ongoing/renewal price NOT published anywhere on public pages as of 2026-07-14 — the '$333/mo therafter' card verified 2026-06-06 has been removed. 'Save $50 on our First Order' banner active.
'Starting at $289' shown on the sema lander card and in the tirz lander's pricing-comparison image ('Tirzepatide (1-Month) $289 — Best Price! 1-Month Plan'); the tirz lander TEXT now contains no dollar prices at all — both the old '$249/mo' hero and '$397/mo therafter' card are gone. Ongoing price quiz-gated = not published.
Unchanged — page title verbatim 'Brightmeds: Choose Your TRT Goal: $75 Per Week, Free Labs'. TRT side-effect disclosures now also cover Enclomiphene and Anastrozole (new adjunct meds).
/products verbatim: '$100 Brightmeds doctor consult fee — Prescription sent to LillyDirect® or your preferred local pharmacy — You'll pay the pharmacy directly (price may vary by pharmacy)'; vials 'Medication cost is billed separately by LillyDirect®'. Drug price not published by Brightmeds.
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What’s included
10rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Brightmeds
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Included
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
10rx
7.1/10
Brightmeds
7.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 10rx | Brightmeds |
|---|---|---|
| Starting Price | ✓$99.67/mo | $100/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | 47 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 10rx
10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.
Read our full 10rx review →About Brightmeds
Brightmeds is a multi-vertical telehealth platform bundling GLP-1 weight loss, TRT for men, and longevity peptides (sermorelin, NAD+, glutathione) under one membership. It offers both compounded GLP-1s — including microdosing protocols — and brand-name Zepbound pens and vials, a rare dual-modality mix. Compounded semaglutide starts at $189/mo and tirzepatide at $289/mo, flat-priced across doses; ongoing renewal pricing isn’t published before the intake quiz. Available in 47 states.
Read our full Brightmeds review →Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to verify
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
Brightmeds
What we like
- One login covers GLP-1, TRT, peptides, and longevity — convenient for men exploring weight loss and hormones
- Offers both compounded GLP-1s and brand-name FDA-approved Zepbound (pens and vials)
- Microdosing protocols available for compounded semaglutide and tirzepatide
- Publishes the FDA compounded-medication disclaimer with explicit 503A and 503B facility mention
- Dispensing pharmacies named in Terms (Beaker Pharmacy and Red Rock Pharmacy)
- Free baseline labs for TRT clients, and a money-back guarantee if not approved
- 47-state footprint (excludes AL, AR, MS) — broader than most TRT-focused platforms
- Tirzepatide is flat-priced across all doses (starting at $289/mo) — no extra cost as you titrate up
Watch-outs
- Pricing isn't itemized on the main pages — you must click through to landers or the application flow
- Brand-name Zepbound carries a separate $100 doctor consult fee on top of drug cost
- No LegitScript certification mentioned on the site
- Named medical director not disclosed
- Trustpilot rating not independently audited
- Multi-vertical bundling can distract patients who only want GLP-1
- Ongoing renewal pricing was removed from the landers — only 'starting at' $189 (sema) and $289 (tirz) first-month prices are published
Our Verdict
Brightmeds edges out 10rx with a higher overall score of 7.4/10 and is particularly strong for compounded or brand GLP-1 bundled with TRT and peptides for men. 10rx remains a solid alternative, especially if you're looking for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.
Choose 10rx if…
You want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.
Choose Brightmeds if…
You want compounded or brand GLP-1 bundled with TRT and peptides for men and a starting price around $100/mo.
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Direct Meds
Listed for transparent disclosure — see FDA warning and BBB complaint pattern before considering
From $249/mo
Get started →Maximus
Men seeking compounded GLP-1 alongside testosterone optimization
From $199.99/mo
Get started →Sesame Care
Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding
From $25/mo
Get started →10rx vs Brightmeds: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.