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10rx vs Avono Health

An in-depth comparison of two leading GLP-1 Providers

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10rx logo

10rx

7.0
★★★3.5

Best for: budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons

Visit 10rx
VS
Avono Health logo

Avono Health

7.2
★★★3.6

Best for: shoppers who want a wide, transparently priced compounded GLP-1 menu including microdose and oral options

Visit Avono Health

10rx and Avono Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $99.67/mo versus $179/mo, and Avono Health edges ahead overall (7.2 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

10rx

Injectablecompounded injection
$99.67/mo
semaglutide

Compounded; GLP-1 options as low as under $100/mo

Injectablecompounded injection
$149.67/mo
tirzepatide

Compounded GLP-1 + GIP

Avono Health

MicrodoseCompounded
$179/mo
semaglutide

Injection (microdose).

MicrodoseCompounded
$199/mo
semaglutide

Oral dissolving tablets (microdose).

MicrodoseCompounded
$219/mo
tirzepatide

Injection (microdose).

MicrodoseCompounded
$229/mo
tirzepatide

Oral dissolving tablets (microdose).

StandardCompounded
$269/mo
semaglutide

Injection. Bundle discounts at 3/6/12 months.

StandardCompounded
$299/mo
semaglutide

Oral capsules.

StandardCompounded
$349/mo
tirzepatide

Injection. Bundle discounts at 3/6/12 months.

StandardCompounded
$379/mo
tirzepatide

Oral capsules.

What’s included

10rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Avono Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

7.0/10

Overall

Avono Health

7.2/10

Value25%

8.5A
vs
B
7.0

Effectiveness25%

7.0A
vs
B
7.5

User Experience15%

7.0A
vs
B
7.5

Trust & Safety15%

5.0A
vs
B
6.5

Accessibility10%

7.5A
vs
B
7.5

Support10%

6.0A
vs
B
7.5

Features & Coverage

Feature10rxAvono Health
Starting Price$99.67/mo$179/mo
Features8 features6 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 10rx

10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.

Read our full 10rx review →

About Avono Health

Fully online compounded GLP-1 telehealth with transparent, tiered pricing — microdose and standard semaglutide and tirzepatide in both injection and oral forms — plus US-licensed clinicians, 24/7 messaging support, and free discreet shipping.

Read our full Avono Health review →

Pros & Cons

10rx

What we like

  • Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
  • Free online health quiz with board-certified telehealth doctors reviewing eligibility
  • Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
  • Says it ships to all 50 states with discreet delivery from licensed pharmacy partners

Watch-outs

  • Doesn't publish its legal operating entity, so accountability is hard to verify
  • Pharmacy partners are described as licensed but none are named
  • No terms-of-service page is posted, and FAQ answers load only via script
  • Compounded semaglutide and tirzepatide only — no brand-name or oral options
  • No LegitScript or third-party accreditation is shown on the site

Avono Health

What we like

  • Transparent tiered pricing from $179/mo (microdose semaglutide injection)
  • Full compounded range — semaglutide and tirzepatide, injection and oral, microdose and standard
  • Free and discreet shipping; 24/7/365 messaging support; 100% online
  • US-licensed clinicians and pharmacies; bundle discounts at 3/6/12 months

Watch-outs

  • Medications are compounded, not FDA-approved brand-name
  • Compounding pharmacy not publicly named
  • State availability not published
  • Newer brand with limited independent review history

Our Verdict

Winner: Avono Health

Avono Health edges out 10rx with a higher overall score of 7.2/10 and is particularly strong for shoppers who want a wide, transparently priced compounded GLP-1 menu including microdose and oral options. 10rx remains a solid alternative, especially if you're looking for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.

Choose 10rx if…

You want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.

Choose Avono Health if…

You want shoppers who want a wide, transparently priced compounded GLP-1 menu including microdose and oral options and a starting price around $179/mo.

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10rx vs Avono Health: FAQ

Key terms, explained

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