Best PT-141 Providers in 2026 — Ranked & Reviewed
PT-141 (bremelanotide) is prescribed for low sexual desire and works through the central melanocortin pathway rather than blood flow, which is what distinguishes it from the ED medications it often sits alongside. It requires a prescription. Every provider below prescribes it through a licensed clinician and is scored on the same dimensions as the rest of our catalog.
28 providers compared
New to PT-141? Read our full PT-141 guide — evidence, dosing, safety and side effects.
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28 pt-141 providers compared · independently scored against our six-factor methodology.
Compare the top providers at a glance
Logos, our editorial rating, price, medications, and coverage — the fastest way to narrow the list.
- ★ Editor's Pick
the lowest all-in monthly price we have verified on compounded semaglutide, labs included
From /moCheck pricingCoverage36 statesMedicationsBPC-157GHK-CuGlutathioneGonadorelinkpvMOTS-cnad-plusPT-141retatrutideSermorelinTB-500Tesamorelin - Nationwide Coverage
Science-forward GLP-1 and peptide care, flat-rate dosing, built-in follow-up
From /moCheck pricingCoverage50 statesMedicationsGHK-CuGlutathioneNAD+PT-141Sermorelin Bryan Johnson's longevity brand: compounded microdose GLP-1 from $167/mo
From /moCheck pricingCoverageCheck intakeMedicationsGlutathioneNAD+PT-141Sermorelincompounded and brand-name GLP-1 plus a longevity stack on one platform
From /moCheck pricingCoverageCheck intakeMedicationsGHK-CuGlutathioneNAD+PT-141SermorelinNeedle-free, microdosed compounded GLP-1 with lab-monitored care
From /moCheck pricingCoverageCheck intakeMedicationsBPC-157CJC-1295 / IpamorelinGHK-CuIpamorelinNAD+PT-141SermorelinTB-500compounded GLP-1 within a lab-driven longevity and hormone clinic
From /moCheck pricingCoverageCheck intakeMedicationsGHK-CuGlutathioneNAD+PT-141Sermorelinphysician-led compounded GLP-1 with labs, follow-up, and peptide options
From /moCheck pricingCoverageCheck intakeMedicationsNAD+SermorelinGlutathioneGonadorelinPT-141patients prioritizing regulatory compliance in the compounded space
From /moCheck pricingCoverageCheck intakeMedicationsBPC-157NAD+PT-141TB-500
| Provider | Rating | From /mo | Medications | Coverage | |
|---|---|---|---|---|---|
★ Editor's Pick the lowest all-in monthly price we have verified on compounded semaglutide, labs included | Check pricing | BPC-157GHK-CuGlutathioneGonadorelinkpvMOTS-cnad-plusPT-141retatrutideSermorelinTB-500Tesamorelin | 36 states | Visit → | |
Nationwide Coverage Science-forward GLP-1 and peptide care, flat-rate dosing, built-in follow-up | Check pricing | GHK-CuGlutathioneNAD+PT-141Sermorelin | 50 states | Visit → | |
 Bryan Johnson's longevity brand: compounded microdose GLP-1 from $167/mo | Check pricing | GlutathioneNAD+PT-141Sermorelin | Check intake | Visit → | |
 compounded and brand-name GLP-1 plus a longevity stack on one platform | Check pricing | GHK-CuGlutathioneNAD+PT-141Sermorelin | Check intake | Visit → | |
 Needle-free, microdosed compounded GLP-1 with lab-monitored care | Check pricing | BPC-157CJC-1295 / IpamorelinGHK-CuIpamorelinNAD+PT-141SermorelinTB-500 | Check intake | Visit → | |
 compounded GLP-1 within a lab-driven longevity and hormone clinic | Check pricing | GHK-CuGlutathioneNAD+PT-141Sermorelin | Check intake | Visit → | |
 physician-led compounded GLP-1 with labs, follow-up, and peptide options | Check pricing | NAD+SermorelinGlutathioneGonadorelinPT-141 | Check intake | Visit → | |
PE PeptidesRxpatients prioritizing regulatory compliance in the compounded space | Check pricing | BPC-157NAD+PT-141TB-500 | Check intake | Visit → |
Providers that don’t post pricing up front score lower on Value and carry a cost-transparency note in their review. Read the full methodology →
Detailed Reviews
A note on prices below: any dollar figure in these provider summaries refers to that clinic’s GLP‑1 weight-loss program, not to PT-141. The PT-141 price is the one beside each clinic in the comparison table above, read from that clinic’s own product page. Where it reads “Check pricing”, the clinic prescribes PT-141 but publishes no price for it — you are quoted after the consultation.
Pepti
Best for: the lowest all-in monthly price we have verified on compounded semaglutide, labs included
Pepti is a Delaware-registered telehealth platform selling doctor-prescribed compounded peptides and GLP-1s across 36 states. Injectable semaglutide is $99 a month all-in and tirzepatide $199, each covering medication, physician review, baseline labs, refill management and shipping in a single flat price that does not rise with dose. The catalogue runs to more than 120 products across weight loss, hormones and TRT, recovery, cognitive and skin categories, plus at-home bloodwork. Pepti is a platform, not a prescriber, and does not bill insurance.
Score Breakdown
Pros
- ✓At $99/mo all-in, injectable semaglutide is among the cheapest verified prices in our catalogue.
- ✓States plainly that all doses cost one flat monthly price, so titrating up never raises the bill.
- ✓Publishes a page for each of the 36 states it serves, and the page count matches its claim exactly.
- ✓Names the reviewing physician, Dr. Gene Lee MD, and discloses pepti LLC as the Delaware operating entity.
Cons
- ✗The homepage shows an "FDA Cleared" badge beside peptide therapy, though product pages correctly say compounded drugs are not FDA-approved.
- ✗Neither the 503A nor the 503B compounding pharmacy is named, so you cannot check who dispenses.
- ✗The listed address, a Newark Delaware suite, is a shared registered-agent address rather than a clinical office.
- ✗Cash-pay only with no insurance billing, and the oral formulations jump to $249 and $399 a month.
YourHealthRx
Best for: Science-forward GLP-1 and peptide care, flat-rate dosing, built-in follow-up
YourHealthRx is a scientist-founded peptide and GLP-1 telehealth platform available in all 50 states and DC via a multi-state (IMLC) clinician network. Compounded semaglutide and tirzepatide come as a weekly injectable (with B12) or a daily oral tablet, at a flat subscription price that doesn't change with your dose - injectable semaglutide ~$170/mo and tirzepatide ~$210/mo ongoing. It also offers a broad peptide catalog plus lab testing. Prescribing runs through partner clinical workflows; compounded meds aren't FDA-approved, the pharmacy isn't named, and no LegitScript is shown.
Score Breakdown
Pros
- ✓Available in all 50 states and DC through a multi-state (IMLC) licensed clinician network
- ✓Compounded semaglutide and tirzepatide in two formats - weekly injectable (with B12) or daily oral dissolving tablet
- ✓Flat subscription price that doesn't change as your dose increases (no titration penalty)
- ✓Science-forward, clinician-led, with built-in follow-up, lab testing, and a broad peptide and longevity catalog (BPC-157, TB-500, sermorelin, NAD+)
- ✓Transparent, education-first positioning with published medical disclaimer, privacy, and terms
Cons
- ✗Eligibility and prescribing run through partner clinical workflows - YourHealthRx is the platform, not the prescriber or pharmacy
- ✗Compounded medications are not FDA-approved - not brand Wegovy, Ozempic, Zepbound, or Mounjaro
- ✗The compounding pharmacy partner is not named ('transparent sourcing' claimed but no pharmacy disclosed)
- ✗Headline prices include a first-month intro rate; ongoing monthly cost is higher (semaglutide ~$170, tirzepatide ~$210)
- ✗No LegitScript certification displayed
Immortals
Best for: Bryan Johnson's longevity brand: compounded microdose GLP-1 from $167/mo
Immortals is a LegitScript-certified longevity telehealth platform founded by Bryan Johnson, offering compounded semaglutide (Semaglutide/Glycine/B12) and tirzepatide (Tirzepatide/Glycine/B12) as microdose weekly injections. Every subscription includes physician review within 72 hours, prescription fulfillment from licensed U.S. pharmacies, discreet shipping, and unlimited provider messaging for 12 months. Semaglutide starts at $167/month and tirzepatide at $180/month (promotional, billed quarterly). HSA/FSA reimbursable; no insurance required.
Score Breakdown
Pros
- ✓LegitScript certified (ID 50458743) with board-certified U.S. physician review within 72 hours
- ✓Physician consult + prescription bundled in price — 'You pay for treatment. That's it' with no added fees
- ✓Competitive pricing: semaglutide microdose from $167/month, tirzepatide from $180/month (promotional)
- ✓Unlimited provider messaging for 12 months included; video consults available
- ✓Founded by Bryan Johnson and Kate Tolo; clinical lead Dr. Carl Seger, M.D. (preventive/longevity medicine)
Cons
- ✗Microdose framing uses sub-clinical doses — lower weight-loss efficacy than standard GLP-1 protocols
- ✗Quarterly commitment only — 3-month minimum, paid upfront ($501–$540/quarter); no monthly flexibility
- ✗State availability not publicly listed; 'eligible U.S. states' with no specific state list
- ✗Labs not included; baseline bloodwork protocol not disclosed on any public page
- ✗Compounding pharmacy not named; no 503A/503B accreditation details disclosed
Kin Meds
Best for: compounded and brand-name GLP-1 plus a longevity stack on one platform
Kin Meds is a LegitScript-verified telehealth platform offering both compounded GLP-1s (semaglutide from $199/mo, tirzepatide from $249/mo) and brand-name FDA-approved options including Wegovy injection and pill, Zepbound and Foundayo from $149/mo. Beyond weight loss, it bundles a longevity and wellness menu — Sermorelin, NAD+, glutathione, TRT, plus hair, skin and sexual health — so members can manage multiple protocols on one account.
Score Breakdown
Pros
- ✓Publicly lists $199/mo compounded semaglutide and $249/mo compounded tirzepatide
- ✓Brand-name options too — Wegovy injection and pill, Zepbound, Foundayo from $149/mo entry pricing
- ✓LegitScript verified
- ✓Clearly identifies itself as the intake platform and a licensed third-party pharmacy as the dispenser
- ✓Broad longevity menu (Sermorelin, NAD+, Glutathione) plus TRT, hair, skin, and sexual health
- ✓Telehealth flow clearly disclosed: questionnaire, provider review, tailored plan, ongoing support
Cons
- ✗Legal entity name and state of incorporation not publicly disclosed
- ✗The third-party pharmacy partner isn't named, and Kin Meds isn't itself a licensed pharmacy
- ✗Per-state availability not listed
- ✗$149/mo brand pricing is the insured entry tier — cash-pay patients should expect higher real costs
- ✗Lab work and dose-titration support not clearly described
- ✗Breadth across 8+ categories signals a broad DTC platform, not a GLP-1 specialist
Telos Rx
Best for: Needle-free, microdosed compounded GLP-1 with lab-monitored care
Telos Rx is a compounded telehealth platform (Superior Health Solutions LLC) offering GLP-1 weight loss alongside longevity, recovery, and sexual-health peptides. Its GLP-1 line includes compounded semaglutide and tirzepatide injections plus needle-free sublingual and microdosed tirzepatide, with provider dose adjustments, lab monitoring, free discreet shipping, FSA/HSA, and cancel-anytime. Headline prices are first-month intro rates (from $49); ongoing cost is higher. Compounded meds are not FDA-approved; pharmacy and states unpublished; no LegitScript shown.
Score Breakdown
Pros
- ✓Multiple GLP-1 modalities: compounded semaglutide and tirzepatide injections plus needle-free sublingual and microdosed tirzepatide
- ✓Provider-led dose adjustments and lab monitoring as your protocol changes
- ✓Free discreet, temperature-controlled shipping (no Telos branding on the outside)
- ✓FSA/HSA eligible and cancel anytime in one click
- ✓Trustpilot rating of 4.9; full compliance suite published (Privacy, Terms, HIPAA, Shipping & returns)
- ✓Integrated care team spanning weight loss, longevity, recovery, and sexual health (peptide-led)
Cons
- ✗Headline pricing is 'first month low as' intro pricing (semaglutide $49, tirzepatide $99) — ongoing monthly cost is higher and shown during intake
- ✗Compounded medications are not FDA-approved (the site discloses this) — not brand Wegovy, Ozempic, Zepbound, or Mounjaro
- ✗Compounding pharmacy partner is not named
- ✗State-availability list is not published
- ✗No LegitScript certification displayed
How to choose a PT-141 provider
PT-141 (bremelanotide) is the one molecule in this category with a real FDA approval — as Vyleesi, for hypoactive sexual desire disorder in premenopausal women. Most telehealth clinics sell a compounded version, often to men, which is off-label use of an approved molecule.
What to look for
- Know whether you are getting Vyleesi or a compound. The approved autoinjector and a compounded vial are not the same product, are not priced the same, and do not carry the same labeling. A clinic should say plainly which one it dispenses.
- On-demand dosing, not daily. PT-141 is taken before anticipated activity, not on a daily schedule. A clinic selling it as a daily regimen has the dosing model wrong.
- Blood-pressure screening. Bremelanotide transiently raises blood pressure and lowers heart rate, and is contraindicated in uncontrolled hypertension or known cardiovascular disease. A clinic that never asks is skipping the main safety check.
Red flags to avoid
- “Research peptides” sold without a prescriber. Vials labelled “for research use only — not for human consumption” are sold outside the drug-approval system entirely, with no verified identity, purity, or sterility. Every peptide in this category is prescription-only in the US; if no licensed clinician is writing a prescription, you are not buying the same product.
- No named 503A or 503B compounding pharmacy. There is no FDA-approved finished product for these peptides, so every legitimate dose comes from a compounding pharmacy. A clinic that will not name the pharmacy it dispenses through is asking you to trust an unverifiable supply chain.
- “FDA-approved” claimed for a compounded peptide. Compounded drugs are not FDA-approved, and saying otherwise is a marketing violation, not a technicality. Some peptides once held an approval for a different indication in a discontinued brand — that is not the same as the compounded product being approved.
- Outcome claims with no trial behind them. Most peptides in this category have mechanistic or early-phase evidence, not randomized outcome trials. A clinic promising a specific fat-loss, muscle, or anti-aging result is selling ahead of the evidence — check our evidence review for the molecule before you commit.
- No baseline labs or follow-up for hormone-axis peptides. Growth-hormone secretagogues raise IGF-1, which is the point and also the thing to monitor. A clinic that never measures it cannot tell whether you are responding or over-dosed.
Every provider ranked above is scored against these criteria across our six-dimension methodology, and prices are re-verified against each provider’s live site.
How we rank & what counts as “legit”
Every provider in this ranking is scored against our published six-factor rubric[1] — value, effectiveness, user experience, trust & safety, accessibility, and support.
Brand-name Wegovy, Zepbound, Ozempic, and Mounjaro are separately FDA-approved under their own NDA numbers[4][5]. Published Phase 3 efficacy for semaglutide 2.4 mg (~14.9% mean weight loss over 68 weeks) comes from the STEP 1 trial[6], and for tirzepatide (~20.9% at the 15 mg dose over 72 weeks) from SURMOUNT-1[7]; the SURMOUNT-5 head-to-head published in 2025 compared the two directly[8].
Insurance coverage for anti-obesity medications varies widely by state Medicaid program and commercial plan[9][10]. Compounded and brand-name GLP-1s are generally FSA/HSA eligible with a prescription under IRS Publication 502[11].
Frequently Asked Questions
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- 503A pharmacy · Pharmacy and drug forms
- 503A vs 503B (pharmacy compounding) · Pharmacy and drug forms
- 503B outsourcing facility · Pharmacy and drug forms
Sources & methodology — as of August 2026
- 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)— WeightLossRankings.org.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 5.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 8.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.
- 9.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 10.CMS — Medicaid prescription drug coverage policy (state-by-state)— Centers for Medicare & Medicaid Services.
- 11.IRS Publication 502 — Medical and Dental Expenses (HSA/FSA eligibility)— Internal Revenue Service.