Compounded Semaglutide Providers in 2026 — Ranked & Reviewed
Compounded semaglutide is a low-cost alternative to brand-name Wegovy and Ozempic, made by 503A and 503B pharmacies under physician supervision. We ranked the most reputable telehealth clinics offering compounded semaglutide in 2026 by price, pharmacy verification, clinical care, and shipping. Every provider on this list ships nationwide.
Lowest verified price: $49/mo411 providers compared
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411 compounded semaglutide providers compared · independently scored against our six-factor methodology.
Compare the top providers at a glance
Logos, our editorial rating, price, medications, and coverage — the fastest way to narrow the list.
- ★ Editor's Pick
best overall value
From /mo$99Flat at every doseCoverage50 statesMedicationsSemaglutideTirzepatide - Nationwide Coverage
mainstream telehealth GLP-1 access
From /mo$99Coverage50 statesMedicationsSemaglutideTirzepatide - Best Budget
the lowest flat medication price if you can absorb an annual membership fee
From /mo$59Flat at every doseCoverageCheck intakeMedicationsSemaglutideTirzepatide lab-monitored compounded GLP-1 with mandatory video visit
From /mo$112Flat at every doseCoverage39 statesMedicationsSemaglutideTirzepatidemainstream telehealth GLP-1 access
From /mo$99Flat at every doseCoverage50 statesMedicationsSemaglutideTirzepatide- Transparent Pricing
physician-led, pharmacy-transparent compounded GLP-1 with brand-name options
From /mo$249Coverage50 statesMedicationsSemaglutideTirzepatide budget-conscious shoppers
From /mo$93CoverageCheck intakeMedicationsSemaglutideTirzepatidecompounded semaglutide and tirzepatide at a flat monthly price
From /mo$133Flat at every doseCoverageCheck intakeMedicationsSemaglutideTirzepatide
| Provider | Rating | From /mo | Medications | Coverage | |
|---|---|---|---|---|---|
★ Editor's Pick best overall value | $99 Flat pricing | SemaglutideTirzepatide | 50 states | Visit → | |
Nationwide Coverage mainstream telehealth GLP-1 access | $99 | SemaglutideTirzepatide | 50 states | Visit → | |
Best Budget the lowest flat medication price if you can absorb an annual membership fee | $59 Flat pricing | SemaglutideTirzepatide | Check intake | Visit → | |
 lab-monitored compounded GLP-1 with mandatory video visit | $112 Flat pricing | SemaglutideTirzepatide | 39 states | Visit → | |
 mainstream telehealth GLP-1 access | $99 Flat pricing | SemaglutideTirzepatide | 50 states | Visit → | |
Transparent Pricing physician-led, pharmacy-transparent compounded GLP-1 with brand-name options | $249 | SemaglutideTirzepatide | 50 states | Visit → | |
 budget-conscious shoppers | $93 | SemaglutideTirzepatide | Check intake | Visit → | |
 compounded semaglutide and tirzepatide at a flat monthly price | $133 Flat pricing | SemaglutideTirzepatide | Check intake | Visit → |
Providers that don’t post pricing up front score lower on Value and carry a cost-transparency note in their review. Read the full methodology →
Detailed Reviews
CoreAge Rx
Verified partnerBest for: best overall value
CoreAge Rx offers LegitScript-certified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.
Score Breakdown
Pros
- ✓LegitScript certified — rigorous pharmacy standards
- ✓Free 2-day shipping nationwide
- ✓Both semaglutide and tirzepatide available
- ✓Lowest per-month pricing in the compounded segment
- ✓24/7 support team
- ✓All 50 states covered
Cons
- ✗Compounded only — no brand-name Ozempic or Wegovy
- ✗Newer brand with fewer independent reviews than legacy players
Found
Verified partnerBest for: mainstream telehealth GLP-1 access
Personalized weight care platform with a self-pay membership model plus medication costs.
Score Breakdown
Pros
- ✓Aggressively low monthly pricing
- ✓Both semaglutide and tirzepatide available
- ✓Compounded GLP-1 access
Cons
- ✗Limited public information on program details
Collective
Verified partnerBest for: the lowest flat medication price if you can absorb an annual membership fee
Collective (collective.org) is a membership-based telehealth platform from the founder of Thrive Market, selling compounded semaglutide and tirzepatide at a flat price on every dose. Medication is billed separately from a required annual membership, and the program bundles unlimited clinician messaging, dietitian access and express cold shipping.
Score Breakdown
Pros
- ✓The lowest published compounded GLP-1 medication prices we track — $59/month semaglutide and $69/month tirzepatide
- ✓Flat pricing at every dose, so titrating up does not raise the bill
- ✓Unlimited clinician messaging and registered-dietitian access are included rather than upsold
- ✓21-day free trial on the membership before the annual fee is charged
Cons
- ✗The advertised $59 and $69 exclude a mandatory $199 annual membership — the real first-year cost is $907 and $1,027
- ✗Membership fees are non-refundable and no partial-period refunds are given
- ✗Compounding pharmacies are described only as 'independent, third-party licensed pharmacies' and are never named
- ✗State availability is not published on the marketing site
Enhance MD
Verified partnerBest for: lab-monitored compounded GLP-1 with mandatory video visit
Enhance MD pairs compounded semaglutide and tirzepatide with mandatory baseline metabolic labs at Quest Diagnostics and a synchronous video visit with a board-certified clinician — a more rigorous onboarding than the async-only compounded GLP-1 model most telehealth providers use. Three tiers (Core semaglutide, Advanced tirzepatide, Elite combined) plus $100-off-first-order intro pricing ($112 first month on Core with code SUMMER100).
Score Breakdown
Pros
- ✓Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
- ✓Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
- ✓Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
- ✓Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
- ✓Intro pricing via $100 off your first order (code SUMMER100): $112 Core, $180 Advanced, $222 Elite first month
- ✓Unlimited clinician messaging and dose-adjustment support included
Cons
- ✗Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- ✗Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
- ✗Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
- ✗No insurance accepted — cash pay, HSA/FSA eligible
- ✗Intro discount applies only to the first order — ongoing rates are $212–$322/mo on 12-month plans, or $249–$379/mo month-to-month
bmiMD
Verified partnerBest for: mainstream telehealth GLP-1 access
Medical weight loss clinic offering GLP-1 prescriptions through telehealth.
Score Breakdown
Pros
- ✓Both semaglutide and tirzepatide available
Cons
- ✗Cheapest advertised rates require a 12-month prepaid plan — month-to-month is $129 for semaglutide and $139 for sermorelin injection
How to choose a compounded semaglutide provider
Compounded semaglutide is a lower-cost alternative to Wegovy and Ozempic, made by 503A/503B pharmacies. It uses the same active ingredient, but it is not FDA-approved, so the pharmacy behind it is everything.
What to look for
- 503A or 503B pharmacy, named. The provider should name its compounding pharmacy and its accreditation. Unnamed 'US-based pharmacy partners' with no detail is a transparency gap.
- Injectable over oral. Injectable compounded semaglutide mirrors the studied product. Oral/sublingual compounded versions have far weaker absorption evidence — treat bold oral claims with caution.
- No surprise additives. Some pharmacies add B6/B12 or other agents. That's not inherently bad, but you should know exactly what's in the vial before you start.
Red flags to avoid
- No named pharmacy or LegitScript listing. A legitimate compounded-GLP-1 provider names its 503A/503B pharmacy partner and carries LegitScript certification. If neither is disclosed, you can't verify what you're injecting.
- Async-only, no real clinician review. A prescriber should review your intake and be reachable for dose questions. Instant approval with no way to reach a clinician is a safety gap.
- Teaser pricing that hides the real cost. A low 'first month' price that jumps at higher doses, or a membership fee stacked on top of the medication, can double the true monthly total. Confirm the ongoing, all-in price before you pay.
- Weight-loss claims for B12, MIC, or HCG shots. Only GLP-1 injections have trial evidence for weight loss. A clinic selling B12, lipotropic, or HCG shots as a weight-loss treatment is a red flag.
Every provider ranked above is scored against these criteria across our six-dimension methodology, and prices are re-verified against each provider’s live site.
How we rank & what counts as “legit”
Every provider in this ranking is scored against our published six-factor rubric[1] — value, effectiveness, user experience, trust & safety, accessibility, and support. Compounded GLP-1s from licensed 503A and 503B pharmacies are legal under federal compounding law[2], with additional tolerances historically allowed while semaglutide and tirzepatide were on the FDA Drug Shortage List[3].
Brand-name Wegovy, Zepbound, Ozempic, and Mounjaro are separately FDA-approved under their own NDA numbers[4][5]. Published Phase 3 efficacy for semaglutide 2.4 mg (~14.9% mean weight loss over 68 weeks) comes from the STEP 1 trial[6], and for tirzepatide (~20.9% at the 15 mg dose over 72 weeks) from SURMOUNT-1[7]; the SURMOUNT-5 head-to-head published in 2025 compared the two directly[8].
Insurance coverage for anti-obesity medications varies widely by state Medicaid program and commercial plan[9][10]. Compounded and brand-name GLP-1s are generally FSA/HSA eligible with a prescription under IRS Publication 502[11].
Frequently Asked Questions
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Wegovy · Drugs and brands
- Ozempic · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- 503B outsourcing facility · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- FDA Drug Shortage List · Insurance and regulatory
Sources & methodology — as of October 2026
- 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)— WeightLossRankings.org.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 5.FDA — Zepbound (tirzepatide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.SURMOUNT-1 Trial — Tirzepatide Once Weekly for the Treatment of Obesity (Jastreboff AM et al.)— New England Journal of Medicine.PMID: 35658024.
- 8.SURMOUNT-5 Trial — Tirzepatide vs. Semaglutide Head-to-Head in Obesity (Garvey WT et al.)— New England Journal of Medicine.PMID: 40334173.
- 9.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 10.CMS — Medicaid prescription drug coverage policy (state-by-state)— Centers for Medicare & Medicaid Services.
- 11.IRS Publication 502 — Medical and Dental Expenses (HSA/FSA eligibility)— Internal Revenue Service.