Vytora Health vs Yes Clinic
An in-depth comparison of two leading GLP-1 Providers
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Vytora Health
Best for: compounded or brand-name GLP-1 with named pharmacy partners, 50 states
Visit Vytora Health →Yes Clinic
Best for: flat per-dose pricing, and seeing every price without a quiz or an account
Visit Yes Clinic →Vytora Health and Yes Clinic are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Yes Clinic starts lower at $129/mo versus $150/mo, and Vytora Health edges ahead overall (8.4 vs 7.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Vytora Health
Yes Clinic
$387 for 3 months = $129/mo. 6 months is $699 = $116.50/mo and is labelled "price locked". No single-month plan renders. Flat at every dose.
$447 for 3 months and $894 for 6 months both work out at $149/mo, "price locked". No single-month plan renders. Flat at every dose.
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What’s included
Vytora Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Yes Clinic
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Vytora Health
8.4/10
Yes Clinic
7.8/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Vytora Health | Yes Clinic |
|---|---|---|
| Starting Price | $150/mo | ✓$129/mo |
| Features | ✓8 features | 6 features |
| States Available | 51 | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Vytora Health
Vytora Health is a 50-state-plus-DC telehealth platform offering compounded semaglutide and tirzepatide alongside brand-name Mounjaro and Zepbound, plus NAD+ and sermorelin peptides. It names its pharmacy partners publicly — Vials Pharmacy and Greenwich Biosciences — and discloses its operating physician group, uncommon transparency for the category. Compounded semaglutide runs $180/mo ($150 on a 3-month bundle) and tirzepatide $249/mo ($200 bundled).
Read our full Vytora Health review →About Yes Clinic
Yes Clinic sells compounded semaglutide and tirzepatide at one flat price that does not rise as your dose is titrated up — $129/mo for semaglutide and $149/mo for tirzepatide, with the consultation, shipping and membership all at $0. Every price is published on the product page without a quiz or an account. The trade-off is that the smallest plan is a three-month prepay charged upfront.
Read our full Yes Clinic review →Pros & Cons
Vytora Health
What we like
- All 50 states plus DC, with per-state video-vs-audio compliance disclosed
- Both compounded and brand-name options on one platform — uncommon
- LegitScript Approved and HIPAA compliant
- Pharmacy partners named publicly: Vials Pharmacy (TX) and Greenwich Biosciences
- Operating entity disclosed: Wasef Health, PC (Pinellas Park, FL)
- Competitive monthly pricing ($180 sema / $249 tirz) plus a 3-month bundle saving 17%
- Brand-name Mounjaro and Zepbound available at $1,399/mo for FDA-approved options
Watch-outs
- Brand-name Mounjaro/Zepbound at $1,399/mo is near retail — insured patients may do better via LillyDirect Self Pay ($449-$699/mo)
- Compounded tirzepatide at $249/mo is mid-market, above the $149-199 floor
- Dose tiers aren't broken out — 'all doses included' means low-dose patients pay the same as high-dose
- Initial consultation cost not shown on the public pricing page
- Limited per-prescriber state licensure detail
Yes Clinic
What we like
- Flat price at every dose — $129/mo semaglutide, $149/mo tirzepatide, and it does not climb as you titrate
- At $129/mo semaglutide sits only $20 below tirzepatide, so stepping up costs little
- "Every price is on this page. No quiz and no account needed to see it" — no email wall to see cost
- Consultation ($30), shipping and membership are all listed at $0: "the price on the tile is the whole price"
- Full refund if you cancel before the pharmacy dispenses; cancel yourself from your account
- Bilingual site with a working EN/ES toggle
Watch-outs
- Smallest plan is a 3-month prepay — $387 or $447 charged upfront, not a monthly bill
- Their live Terms of Use still contains an unfilled template placeholder: governed by the laws of the State of {GOVERNING_LAW_STATE}
- No pharmacy partner is named despite a "LegitScript Certified" banner in the footer
- No state list published: "Services are not available in all states"
- Product pages served different prices in source HTML than they render, so quote the figure you see on screen
- Support is email-only; no phone number published
Our Verdict
Vytora Health edges out Yes Clinic with a higher overall score of 8.4/10 and is particularly strong for compounded or brand-name GLP-1 with named pharmacy partners, 50 states. Yes Clinic remains a solid alternative, especially if you're looking for flat per-dose pricing, and seeing every price without a quiz or an account.
Choose Vytora Health if…
You want compounded or brand-name GLP-1 with named pharmacy partners, 50 states and a starting price around $150/mo.
Choose Yes Clinic if…
You want flat per-dose pricing, and seeing every price without a quiz or an account and a starting price around $129/mo.
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Get started →Vytora Health vs Yes Clinic: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.