Major trials

STEP-TEENS

The pivotal Phase 3 trials and post-approval cardiovascular, kidney, and sleep-apnea outcome studies.

Definition

Trial of semaglutide 2.4 mg in adolescents 12-17 with obesity (Weghuber et al, NEJM 2022). Mean weight reduction 16.7% vs 0.6% placebo. Pediatric trials do not measure facial appearance as an outcome.

STEP-TEENS adolescent semaglutide

Definition curated by Weight Loss Rankings — sourced from FDA labels and peer-reviewed PubMed literature, never AI-generated summaries.

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