IWQOL-Lite-CT

Definition

The Impact of Weight on Quality of Life-Lite Clinical Trials version — a 20-item patient-reported outcome questionnaire validated for use in obesity drug trials. Scored 0-100, higher is better; physical-function and psychosocial subdomains are reported separately. Clinically meaningful improvement threshold is ~14.6 points. STEP-1 and SURMOUNT-1 both reported large IWQOL-Lite-CT gains, used by FDA in evaluating quality-of-life claims for Wegovy and Zepbound labeling.

STEP-1 quality-of-life endpoint →

Definition curated by Weight Loss Rankings — sourced from FDA labels and peer-reviewed PubMed literature, never AI-generated summaries.

Related terms in Major trials

• STEP-1
• SURMOUNT-1
• SELECT
• FLOW
• SURMOUNT-OSA
• STEP-TEENS
• MACE (Major Adverse Cardiovascular Events)
• KCCQ-CSS (Kansas City Cardiomyopathy Questionnaire — Clinical Summary Score)
• ATTAIN-1

Looking for more depth?

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