Wholesome Clinic vs Vytora Health
An in-depth comparison of two leading GLP-1 Providers
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Wholesome Clinic
Best for: Multi-state telehealth pairing compounded GLP-1 weight loss with integrative psychiatry
Visit Wholesome Clinic →
Vytora Health
Best for: compounded or brand-name GLP-1 with named pharmacy partners, 50 states
Visit Vytora Health →Wholesome Clinic and Vytora Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Wholesome Clinic starts lower at $109/mo versus $150/mo, and Vytora Health edges ahead overall (8.4 vs 7.6 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Wholesome Clinic
Self-pay; $109/$149/$199 per month by dose plan
Self-pay; $149-$199+ per month by dose plan
Self-pay; $249/$299/$349 per month by dose plan
Self-pay; $349/$449/$549 per month by dose plan
Vytora Health
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What’s included
Wholesome Clinic
What the monthly price covers
Medication
Included
Provider visits
Billed separately
Shipping
Not disclosed
Lab work
Not disclosed
Coaching
Not disclosed
Vytora Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Wholesome Clinic
7.6/10
Vytora Health
8.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Wholesome Clinic | Vytora Health |
|---|---|---|
| Starting Price | ✓$109/mo | $150/mo |
| Features | 6 features | ✓8 features |
| States Available | 7 | ✓51 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Wholesome Clinic
Wholesome Clinic is a Frisco, Texas integrative-psychiatry and wellness practice offering medical weight loss via telehealth across seven states. Providers prescribe compounded semaglutide and tirzepatide (oral dissolving tablet or weekly injectable), plus brand Wegovy and Zepbound when clinically appropriate. Self-pay medication runs from $109/month for compounded semaglutide, with a $149 initial evaluation and $75 follow-ups billed separately.
Read our full Wholesome Clinic review →About Vytora Health
Vytora Health is a 50-state-plus-DC telehealth platform offering compounded semaglutide and tirzepatide alongside brand-name Mounjaro and Zepbound, plus NAD+ and sermorelin peptides. It names its pharmacy partners publicly — Vials Pharmacy and Greenwich Biosciences — and discloses its operating physician group, uncommon transparency for the category. Compounded semaglutide runs $180/mo ($150 on a 3-month bundle) and tirzepatide $249/mo ($200 bundled).
Read our full Vytora Health review →Pros & Cons
Wholesome Clinic
What we like
- Publishes standing per-dose self-pay prices for compounded semaglutide and tirzepatide, oral and injectable
- Compounded semaglutide from $109/mo (oral) or $149/mo (injectable); brand Wegovy/Zepbound offered when appropriate
- Telehealth across seven states plus an in-person option at its Frisco, TX office
Watch-outs
- $149 initial evaluation and $75 follow-up visits are billed separately from medication
- Filled through your 'preferred pharmacy' — no single named compounding pharmacy partner
- No LegitScript certification displayed
Vytora Health
What we like
- All 50 states plus DC, with per-state video-vs-audio compliance disclosed
- Both compounded and brand-name options on one platform — uncommon
- LegitScript Approved and HIPAA compliant
- Pharmacy partners named publicly: Vials Pharmacy (TX) and Greenwich Biosciences
- Operating entity disclosed: Wasef Health, PC (Pinellas Park, FL)
- Competitive monthly pricing ($180 sema / $249 tirz) plus a 3-month bundle saving 17%
- Brand-name Mounjaro and Zepbound available at $1,399/mo for FDA-approved options
Watch-outs
- Brand-name Mounjaro/Zepbound at $1,399/mo is near retail — insured patients may do better via LillyDirect Self Pay ($449-$699/mo)
- Compounded tirzepatide at $249/mo is mid-market, above the $149-199 floor
- Dose tiers aren't broken out — 'all doses included' means low-dose patients pay the same as high-dose
- Initial consultation cost not shown on the public pricing page
- Limited per-prescriber state licensure detail
Our Verdict
Vytora Health edges out Wholesome Clinic with a higher overall score of 8.4/10 and is particularly strong for compounded or brand-name GLP-1 with named pharmacy partners, 50 states. Wholesome Clinic remains a solid alternative, especially if you're looking for Multi-state telehealth pairing compounded GLP-1 weight loss with integrative psychiatry.
Choose Wholesome Clinic if…
You want Multi-state telehealth pairing compounded GLP-1 weight loss with integrative psychiatry and a starting price around $109/mo.
Choose Vytora Health if…
You want compounded or brand-name GLP-1 with named pharmacy partners, 50 states and a starting price around $150/mo.
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Get started →Wholesome Clinic vs Vytora Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.