Vytora Health vs WeightlessRx
In our scoring, Vytora Health edges ahead overall (8.4 vs 7.1 out of 10), and WeightlessRx costs less for compounded semaglutide (about $60 a year less).
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Key differences
- Price
- WeightlessRx $174/mo vs Vytora Health $179/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $60 a year less with WeightlessRx)
- Coverage
- Vytora Health 50 states + DC (WeightlessRx doesn't publish a state list)
- Included
- Vytora Health: medication, clinician visits, shipping; WeightlessRx: medication, clinician visits, shipping, coaching

Vytora Health
Best for compounded or brand-name GLP-1 with named pharmacy partners, 50 states
semaglutide
$179
Our score 8.4/10

WeightlessRx
Best for compounded semaglutide or tirzepatide with no membership fee, charged only after a clinician approves you
semaglutide
$174
Our score 7.1/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Vytora Health
WeightlessRx
Price
Semaglutide / month
$179/mo
Better on this row: $174/mo
Semaglutide / year (modeled)
$2,148
Better on this row: $2,088
Tirzepatide / month
Better on this row: $249/mo
$250/mo
Tirzepatide / year (modeled)
Better on this row: $2,988
$3,000
Brand Zepbound / Mounjaro / month
$1,399/mo
Not listed
Coverage
State availability
50 states + DC
List not published
Brand-name access listed
Zepbound / Mounjaro
Not listed
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping, coaching
Terms & safety
Price shown
Before intake
Before intake
Video visit
Not disclosed
Required
Cancel anytime
Yes
Not disclosed
Minimum commitment
None on monthly plans; 3-month plans are billed every 3 months
3-month prepay
Refunds
'All sales are final' for prescription products; refund requests 'reviewed on a case-by-case basis'
Not disclosed
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
August 2026
Every dose and plan: Vytora Health · WeightlessRx
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.

Choose Vytora Health if…
- Lists brand-name Zepbound / Mounjaro, which WeightlessRx doesn't price
- Publishes its full state list (50 states + DC)
- Both compounded and brand-name options on one platform
What to weigh up
- About $60 a year more than WeightlessRx for compounded semaglutide
- Brand-name Mounjaro and Zepbound at $1,399/mo are priced at retail; manufacturer self-pay programs are often cheaper

Choose WeightlessRx if…
- About $60 a year less than Vytora Health for compounded semaglutide at standing prices
What to weigh up
- No published state list; confirm yours at signup
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Vytora Health
8.4/10
WeightlessRx
7.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
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GobyMeds
No-membership, no-auto-renew compounded GLP-1 orders, from about $99/mo on a 3-month bundle
Read full review →From $169/mo
Get started →Ivim Health
Compounded GLP-1 with weekly provider check-ins and health coaches, under a required monthly membership
Read full review →From $65/mo + membership
Get started →From $247/mo
Get started →Vytora Health vs WeightlessRx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.