Vital Step vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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Vital Step
Best for: people who want compounded semaglutide or tirzepatide as an injection or a daily tablet, month to month
Visit Vital Step →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →Vital Step and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $296/mo, and NewSelf edges ahead overall (8.3 vs 6.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Vital Step
$179 first month, then $296/mo. 3, 6 and 12-month supplies are billed upfront: $717, $1,326 and $2,592
$179 first month, then $296/mo. 3, 6 and 12-month supplies are billed upfront: $717, $1,326 and $2,592
$279 first month, then $396/mo. 3, 6 and 12-month supplies are billed upfront: $1,068, $2,022 and $3,918
$279 first month, then $396/mo. 3, 6 and 12-month supplies are billed upfront: $1,068, $2,022 and $3,918
NewSelf
All dosages same price
All dosages same price
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What’s included
Vital Step
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Vital Step
6.3/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Vital Step | NewSelf |
|---|---|---|
| Starting Price | $296/mo | ✓$100/mo |
| Features | 6 features | 6 features |
| States Available | Not disclosed | 49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | ✓ Yes | — |
| FDA Warnings | ✓None | 1 warning |
About Vital Step
Vital Step is a Nevada telehealth company that sells compounded semaglutide and tirzepatide as weekly injections or daily dissolving tablets, prescribed through the Dr. TelX medical group. Month-to-month plans renew at $296 a month for semaglutide and $396 for tirzepatide after a discounted first month. The advertised $161 and $198 figures are the first month of a 6-month plan billed upfront.
Read our full Vital Step review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
Vital Step
What we like
- Offers both semaglutide and tirzepatide, each as a weekly injection or a daily dissolving tablet
- Names its medical group (Dr. TelX) in its terms of service
- Monthly price is described as covering the provider review, dosing guidance, ongoing support and the medication
- Free shipping is advertised on the home page and product pages
- A month-to-month plan is available with no prepay requirement
- Says HSA and FSA funds can be used for eligible expenses
Watch-outs
- The "as low as $161" and "$198" prices are the first month of 6-month plans charged upfront ($1,326 and $2,022)
- After a discounted first month, month-to-month plans renew at $296 for semaglutide and $396 for tirzepatide
- Plan prices appear only after you enter an email address in the intake
- Strict no-refund policy: fees are not refundable in whole or in part, and partial subscription periods are not refunded
- The site lists all 50 states, but its terms exclude Alaska, Arkansas, Louisiana, New Hampshire, Oregon, South Carolina, West Virginia and DC
- The dispensing pharmacy is not named; product pages call the pharmacies "FDA approved"
- The LegitScript badge links to a generic lookup page, and no certification record could be confirmed
- Two home-page testimonials share identical wording, and no independent reviews exist yet
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out Vital Step with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Vital Step remains a solid alternative, especially if you're looking for people who want compounded semaglutide or tirzepatide as an injection or a daily tablet, month to month.
Choose Vital Step if…
You want people who want compounded semaglutide or tirzepatide as an injection or a daily tablet, month to month and a starting price around $296/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
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AgelessRx
Longevity-focused GLP-1 care
From $139/mo
Get started →Willow
Mainstream telehealth GLP-1 access
From $299/mo
Get started →Sesame Care
Brand-name GLP-1s at cash prices, no compounding
From $25/mo
Get started →Vital Step vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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