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Thriving Again vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Thriving Again logo

Thriving Again

6.8
★★★☆☆3.4/5

Best for: Men seeking GLP-1 weight loss alongside hormone, TRT, and peptide optimization in one platform

Visit Thriving Again
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

Thriving Again and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts at $100/mo, and NewSelf edges ahead overall (8.3 vs 6.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Thriving Again

Pricing not publicly listed.

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

Thriving Again

Inclusions not disclosed.

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Thriving Again

6.8/10

Overall

NewSelf

8.3/10

Value25%

6.5A
vs
B
9.0

Effectiveness25%

7.0A
vs
B
8.0

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

6.5A
vs
B
8.3

Accessibility10%

7.0A
vs
B
8.5

Support10%

7.0A
vs
B
7.9

Features & Coverage

FeatureThriving AgainNewSelf
Starting Price$100/mo
Features8 features6 features
States AvailableNot disclosed49
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About Thriving Again

Thriving Again is a US telehealth platform positioned around premium men's health and optimization, with hormone/TRT, peptides, and a GLP-1 weight loss line. It prescribes compounded GLP-1 medication via board-certified, state-licensed providers shipped as pre-filled syringes, with at-home lab testing and 24/7 messaging support. The company advertises availability across all 50 states with 500+ providers and protocols from $149/mo. Compounded products are not FDA-approved or evaluated for safety, effectiveness, or quality. Weight loss is one vertical alongside hormone and peptide care.

Read our full Thriving Again review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

Thriving Again

What we like

  • Compounded GLP-1 with at-home labs and ongoing provider messaging
  • Advertises nationwide coverage with 500+ licensed providers
  • Pre-filled syringe delivery simplifies dosing
  • Combines weight loss with hormone and peptide optimization

Watch-outs

  • No specific GLP-1 dose or monthly pricing published online
  • Weight loss is one vertical alongside men's hormone and TRT care
  • Compounded products are not FDA-approved or evaluated

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out Thriving Again with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Thriving Again remains a solid alternative, especially if you're looking for Men seeking GLP-1 weight loss alongside hormone, TRT, and peptide optimization in one platform.

Choose Thriving Again if…

You want Men seeking GLP-1 weight loss alongside hormone, TRT, and peptide optimization in one platform.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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Thriving Again vs NewSelf: FAQ

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