PlushCare vs Vytora Health
In our scoring, Vytora Health edges ahead overall (8.4 vs 7.0 out of 10), and PlushCare costs less for compounded semaglutide (about $360 a year less).
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Key differences
- Price
- PlushCare $149/mo vs Vytora Health $179/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $360 a year less with PlushCare)
- Coverage
- PlushCare 50 states; Vytora Health 50 states + DC (only Vytora Health: District of Columbia)
- Included
- PlushCare: none of the listed items (not included: medication, clinician visits, labs); Vytora Health: medication, clinician visits, shipping
PlushCare
Best for virtual primary care that can also prescribe GLP-1s
semaglutide
$149
Our score 7.0/10
Vytora Health
Best for compounded or brand-name GLP-1 with named pharmacy partners, 50 states
semaglutide
$179
Our score 8.4/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
PlushCare
Vytora Health
Price
Semaglutide / month
Better on this row: $149/mo
$179/mo
Semaglutide / year (modeled)
Better on this row: $1,788
$2,148
Tirzepatide / month
$399/mo
Better on this row: $249/mo
Tirzepatide / year (modeled)
$4,788
Better on this row: $2,988
Brand Zepbound / Mounjaro / month
Not listed
$1,399/mo
Coverage
State availability
50 states
50 states + DC
Brand-name access listed
Not listed
Zepbound / Mounjaro
Included in the price
None of the listed items
Not included: medication, clinician visits, labs
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Lab work
Required
Not disclosed
Video visit
Required
Not disclosed
Cancel anytime
Not disclosed
Yes
Minimum commitment
Membership
None on monthly plans; 3-month plans are billed every 3 months
Refunds
Not disclosed
'All sales are final' for prescription products; refund requests 'reviewed on a case-by-case basis'
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
October 2026
Show where they differ by stateHide state lists
Only Vytora Health (DC)
- District of Columbia
Every dose and plan: PlushCare · Vytora Health
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 540+ providers' prices on their own sites and email you when tracked prices move.
Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose PlushCare if…
- About $360 a year less than Vytora Health for compounded semaglutide at standing prices
- Appointments with US board-certified physicians, not nurse practitioners only
- Virtual primary care — the same doctor can manage GLP-1s alongside other health needs
What to weigh up
- Not available in District of Columbia
- Price doesn't include medication and clinician visits
Choose Vytora Health if…
- Lists brand-name Zepbound / Mounjaro, which PlushCare doesn't price
- Serves District of Columbia, where PlushCare doesn't
- Price includes medication and clinician visits; PlushCare's doesn't
What to weigh up
- About $360 a year more than PlushCare for compounded semaglutide
- Brand-name Mounjaro and Zepbound at $1,399/mo are priced at retail; manufacturer self-pay programs are often cheaper
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
PlushCare
7.0/10
Vytora Health
8.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
From $139/mo
Get started →From $299/mo
Get started →SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →PlushCare vs Vytora Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring PlushCare and Vytora Health head-to-heads in the same category.
- PlushCare vs Amazon One Medical
- Vytora Health vs Amazon One Medical
- Vytora Health vs CoreAge Rx
- Vytora Health vs Collective
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.