Always verify pricing and state availability on the provider's website before signing up.How our reviews work →

PlexusDx vs CoreAge Rx

An in-depth comparison of two leading GLP-1 Providers

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
PlexusDx logo

PlexusDx

7.0
★★★3.5/5

Best for: nationwide compounded GLP-1 with optional genetic-test personalization

Visit PlexusDx
VS
CoreAge Rx logo

CoreAge Rx

8.3
★★★★4.2/5

Best for: best overall value

Visit CoreAge Rx

PlexusDx and CoreAge Rx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, CoreAge Rx starts lower at $99/mo versus $129/mo, and CoreAge Rx edges ahead overall (8.3 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

PlexusDx

Microdose GLP-1 monthlyCompounded
$129/mo
semaglutide

'Microdose GLP-1 $129/mo All-Inclusive — small weekly dose, lower side effects, entry-level.'

Compounded semaglutide startingCompounded
$149/mo
semaglutide

'Semaglutide Starts at $149/mo All-Inclusive — weekly injection or daily oral.'

Compounded tirzepatide startingCompounded
$249/mo
tirzepatide

'Tirzepatide Starts at $249/mo All-Inclusive — dual-receptor.'

GLP-Squared — semaglutide + tirzepatide in one weekly injectionCompounded
$249/mo
tirzepatide

'PlexusDx Exclusive GLP-Squared — Semaglutide + Tirzepatide. Single weekly injection.' Priced the same as tirzepatide alone.

CoreAge Rx

Injectable, monthly auto-refill (flat across all dosages)Compounded
$99/mo
semaglutide

Re-verified 2026-08-05: homepage + Preventive Longevity section both show "Semaglutide — Starting at $99/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

Injectable, monthly auto-refill (flat across all dosages)Compounded
$149/mo
tirzepatide

Re-verified 2026-08-05: homepage GLP-1 hero + Preventive Longevity section both show "Tirzepatide — Starting at $149/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

Get alerted when GLP-1 prices drop

Join the GLP-1 price-watch list — we re-verify 500+ providers' prices on their own sites and email you when tracked prices move.

What’s included

PlexusDx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Not disclosed

Lab work

Not disclosed

Coaching

Not disclosed

CoreAge Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

PlexusDx

7.0/10

Overall

CoreAge Rx

8.3/10

Value25%

7.0A
vs
B
8.5

Effectiveness25%

7.0A
vs
B
8.5

User Experience15%

7.0A
vs
B
8.5

Trust & Safety15%

6.8A
vs
B
7.8

Accessibility10%

7.5A
vs
B
8.0

Support10%

6.5A
vs
B
8.4

Features & Coverage

FeaturePlexusDxCoreAge Rx
Starting Price$129/mo$99/mo
Features8 features6 features
States Available5050
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About PlexusDx

PlexusDx (plexusdx.com) is a US GLP-1 telehealth platform offering compounded weight-loss medications with licensed providers in all 50 states. Programs include a microdose GLP-1 from $129/month, compounded semaglutide from $149/month, compounded tirzepatide from $249/month, and a combination GLP-Squared protocol. An independent US-licensed clinician reviews each patient via a state-licensed telehealth platform, and medications come from state-licensed pharmacies. PlexusDx is distinctive for an optional Precision Peptide genetic test (151 insights) discounted to $99 after a first order.

Read our full PlexusDx review →

About CoreAge Rx

CoreAge Rx offers LegitScript-verified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.

Read our full CoreAge Rx review →

Pros & Cons

PlexusDx

What we like

  • Licensed providers available in all 50 states
  • Range of options including low-cost microdose GLP-1 from $129/mo
  • Optional Precision Peptide genetic panel adds a personalization angle
  • Independent clinician review via state-licensed telehealth platform
  • Compounded medications from state-licensed pharmacies

Watch-outs

  • Compounded medications only; no FDA-approved brand options
  • Specific compounding pharmacies not named
  • Genetic-panel upsell may not add clinical value for everyone
  • Tirzepatide pricing from $249/mo is higher than budget rivals
  • No insurance accepted

CoreAge Rx

What we like

  • LegitScript certified — rigorous pharmacy standards
  • Free 2-day shipping nationwide
  • Both semaglutide and tirzepatide available
  • Lowest per-month pricing in the compounded segment
  • 24/7 support team
  • All 50 states covered

Watch-outs

  • Compounded only — no brand-name Ozempic or Wegovy
  • Newer brand with fewer independent reviews than legacy players

Our Verdict

Winner: CoreAge Rx

CoreAge Rx edges out PlexusDx with a higher overall score of 8.3/10 and is particularly strong for best overall value. PlexusDx remains a solid alternative, especially if you're looking for nationwide compounded GLP-1 with optional genetic-test personalization.

Choose PlexusDx if…

You want nationwide compounded GLP-1 with optional genetic-test personalization and a starting price around $129/mo.

Choose CoreAge Rx if…

You want best overall value and a starting price around $99/mo.

Ready to start? Vetted GLP-1 providers

Vetted telehealth providers that prescribe GLP-1 online.

No insurance needed · vetted by our editors

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

8.1

RxSpan MD

Physician-led, pharmacy-transparent compounded GLP-1 with brand-name options

8.0

Strut Health

Oral-lozenge compounded GLP-1 access

7.8

Yucca Health

Mainstream telehealth GLP-1 access

PlexusDx vs CoreAge Rx: FAQ

CoreAge Rx is cheaper. Its lowest ongoing monthly cash price is $99/mo, compared with $129/mo for PlexusDx. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
CoreAge Rx scores higher overall at 8.3/10 versus 7.0/10, and is particularly strong for best overall value. That said, PlexusDx is a better fit if you want nationwide compounded GLP-1 with optional genetic-test personalization.
PlexusDx and CoreAge Rx both list availability in 50 states.
CoreAge Rx is an affiliate partner (we may earn a commission on sign-ups through our links); PlexusDx is not. Either way, we rank providers editorially with the same scoring framework and disclose every partnership — being a partner does not buy a higher score.
For Semaglutide, CoreAge Rx is cheaper at $99/mo versus $129/mo at PlexusDx.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring PlexusDx and CoreAge Rx head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.