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Nova vs Amazon One Medical

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Nova

7.0
★★★★☆3.5/5

Best for: Texas and Florida readers who want needle-free GLP-1 options at an all-in price

Visit Nova →
VS
Amazon One Medical logo

Amazon One Medical

8.5
★★★★☆4.3/5

Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery

Visit Amazon One Medical →

Nova and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $156/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Nova

Compounded semaglutide + B12 — weekly injectionCompounded
$198/mo
semaglutide

All-in: medication, shipping and the required Nova Care fee.

Compounded semaglutide RDT — weekly needle-free sublingual tabletCompounded · oral
$156/mo
semaglutide

First 3 months of medication ship and bill together at $269 on provider approval.

Semaglutide oral daily dose — daily sublingual microdose (36 or 145 mcg)Compounded · oral
$169/mo
semaglutide

Provider picks the strength; sublingual mg are not interchangeable with injectable mg.

Compounded tirzepatide + B12 — weekly injectionCompounded
$210/mo
tirzepatide

All-in: medication, shipping and the required Nova Care fee.

Compounded tirzepatide RDT — weekly needle-free sublingual tabletCompounded · oral
$209/mo
tirzepatide

First 2 months of medication ship and bill together at $319 on provider approval.

Tirzepatide oral daily dose — daily sublingual microdoseCompounded · oral
$174/mo
tirzepatide

Daily dual GLP-1 + GIP microdose; sublingual mg are not interchangeable with injectable mg.

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

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What’s included

Nova

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Nova

7.0/10

Overall

Amazon One Medical

8.5/10

Value25%

7.0A
vs
B
8.5

Effectiveness25%

7.5A
vs
B
8.5

User Experience15%

8.0A
vs
B
8.0

Trust & Safety15%

6.5A
vs
B
8.8

Accessibility10%

5.0A
vs
B
9.5

Support10%

7.0A
vs
B
8.0

Features & Coverage

FeatureNovaAmazon One Medical
Starting Price$156/mo✓$149/mo
Features6 features6 features
States Available2✓50
Compounded✓ Yes—
Brand Name—✓ Yes
FSA/HSA Accepted——
FDA WarningsNoneNone

About Nova

Nova (NovaCure LLC) is a Texas- and Florida-only telehealth platform selling compounded semaglutide and tirzepatide in three formats each — weekly injection, weekly needle-free sublingual tablet, and a daily sublingual microdose — alongside hair, sexual-health and peptide programs. Every price is all-in, covering medication, shipping and the required Nova Care fee, and the weight-loss line runs from $156 to $210 a month.

Read our full Nova review →

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

Pros & Cons

Nova

What we like

  • Every price is all-in — medication, shipping and the required Nova Care fee are in the number you see, with no separate membership line
  • Three formats per molecule: weekly injection, weekly needle-free sublingual tablet, and a daily sublingual microdose
  • Six compounded GLP-1 options priced $156 to $210 a month, all shown before you pay
  • States its service area plainly in the footer — Texas and Florida
  • iOS and Android apps for messaging your care team and tracking orders
  • Free refrigerated shipping on every order and no separate consultation fee
  • Discloses clearly that the FDA does not approve compounded medications
  • Tells you plainly that sublingual mg are not interchangeable with injectable mg — a real safety point most sellers skip

Watch-outs

  • Only available in Texas and Florida — most readers cannot buy here at all
  • The two RDT tablets bundle their first months into one upfront charge: $269 for 3 months of semaglutide, $319 for 2 months of tirzepatide
  • Its pricing page splits a $99 membership from medication, but checkout charges a single all-in figure, so the two do not reconcile
  • Pricing page says you're only charged if a provider prescribes; the refund policy says membership fees aren't refunded if they decline
  • The refund policy still refers to patients 'located outside Texas', so it has not been updated since Florida was added
  • The compounding pharmacy is described only as a state-licensed 503A facility and is never named
  • Oral daily strengths are provider-selected (36 or 145 mcg) and the site does not say which you will get

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

Our Verdict

Winner: Amazon One Medical

Amazon One Medical edges out Nova with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. Nova remains a solid alternative, especially if you're looking for Texas and Florida readers who want needle-free GLP-1 options at an all-in price.

Choose Nova if…

You want Texas and Florida readers who want needle-free GLP-1 options at an all-in price and a starting price around $156/mo.

Choose Amazon One Medical if…

You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.

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8.1

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Compounded semaglutide and tirzepatide at a flat monthly price

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Nova vs Amazon One Medical: FAQ

Amazon One Medical is cheaper. Its lowest ongoing monthly cash price is $149/mo, compared with $156/mo for Nova. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Amazon One Medical scores higher overall at 8.5/10 versus 7.0/10, and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. That said, Nova is a better fit if you want Texas and Florida readers who want needle-free GLP-1 options at an all-in price.
Amazon One Medical covers more — 50 states versus 2.
Neither Nova nor Amazon One Medical is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.

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Continue exploring Nova and Amazon One Medical head-to-heads in the same category.

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.