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NexLife vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
NexLife logo

NexLife

7.1
★★★3.6/5

Best for: pharmacy-quality-conscious patients seeking LegitScript + NABP-certified compounded GLP-1

Visit NexLife
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

NexLife and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $145/mo, and NewSelf edges ahead overall (8.3 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

NexLife

Compounded Semaglutide (monthly plan)Compounded
$165/mo
semaglutide
Compounded Semaglutide (12-month plan)Compounded
$145/mo
semaglutide

Plan ladder: $165 monthly, $149/mo 3-mo, $147/mo 6-mo, $145/mo 12-mo. $145 is the 12-month-plan rate, not a promo.

Compounded Tirzepatide (monthly plan)Compounded
$215/mo
tirzepatide
Compounded Tirzepatide (12-month plan)Compounded
$186/mo
tirzepatide

Plan ladder: $215 monthly, $195/mo 3-mo, $190/mo 6-mo, $186/mo 12-mo. $186 is the 12-month-plan rate, not a promo.

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

NexLife

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

NexLife

7.1/10

Overall

NewSelf

8.3/10

Value25%

7.0A
vs
B
9.0

Effectiveness25%

7.0A
vs
B
8.0

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

7.3A
vs
B
8.3

Accessibility10%

7.0A
vs
B
8.5

Support10%

7.4A
vs
B
7.9

Features & Coverage

FeatureNexLifeNewSelf
Starting Price$145/mo$100/mo
Features5 features6 features
States AvailableNot disclosed49
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About NexLife

NexLife is a LegitScript-certified telehealth platform offering compounded semaglutide (from $145/mo) and compounded tirzepatide (from $186/mo). Works exclusively with LegitScript-certified, NABP-accredited pharmacies.

Read our full NexLife review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

NexLife

What we like

  • LegitScript certified platform
  • Works exclusively with LegitScript-certified, NABP-accredited pharmacies — strongest pharmacy trust signal in the dataset
  • Both semaglutide and tirzepatide at competitive pricing
  • Semaglutide from $145/mo on the 12-month plan ($165/mo month-to-month) - among the lowest in the dataset

Watch-outs

  • State availability not publicly disclosed
  • Compounded only — no brand-name options
  • Also covers hormone optimization and longevity
  • Lowest advertised rates ($145 sema / $186 tirz) require a 12-month plan commitment

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out NexLife with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. NexLife remains a solid alternative, especially if you're looking for pharmacy-quality-conscious patients seeking LegitScript + NABP-certified compounded GLP-1.

Choose NexLife if…

You want pharmacy-quality-conscious patients seeking LegitScript + NABP-certified compounded GLP-1 and a starting price around $145/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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NexLife vs NewSelf: FAQ

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