NewSelf vs Wholesome Clinic
An in-depth comparison of two leading GLP-1 Providers
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NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →
Wholesome Clinic
Best for: Multi-state telehealth pairing compounded GLP-1 weight loss with integrative psychiatry
Visit Wholesome Clinic →NewSelf and Wholesome Clinic are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $109/mo, and NewSelf edges ahead overall (8.3 vs 7.6 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
NewSelf
All dosages same price
All dosages same price
Wholesome Clinic
Self-pay; $109/$149/$199 per month by dose plan
Self-pay; $149-$199+ per month by dose plan
Self-pay; $249/$299/$349 per month by dose plan
Self-pay; $349/$449/$549 per month by dose plan
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What’s included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Wholesome Clinic
What the monthly price covers
Medication
Included
Provider visits
Billed separately
Shipping
Not disclosed
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.3/10
Wholesome Clinic
7.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | NewSelf | Wholesome Clinic |
|---|---|---|
| Starting Price | ✓$100/mo | $109/mo |
| Features | 6 features | 6 features |
| States Available | ✓49 | 7 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →About Wholesome Clinic
Wholesome Clinic is a Frisco, Texas integrative-psychiatry and wellness practice offering medical weight loss via telehealth across seven states. Providers prescribe compounded semaglutide and tirzepatide (oral dissolving tablet or weekly injectable), plus brand Wegovy and Zepbound when clinically appropriate. Self-pay medication runs from $109/month for compounded semaglutide, with a $149 initial evaluation and $75 follow-ups billed separately.
Read our full Wholesome Clinic review →Pros & Cons
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Wholesome Clinic
What we like
- Publishes standing per-dose self-pay prices for compounded semaglutide and tirzepatide, oral and injectable
- Compounded semaglutide from $109/mo (oral) or $149/mo (injectable); brand Wegovy/Zepbound offered when appropriate
- Telehealth across seven states plus an in-person option at its Frisco, TX office
Watch-outs
- $149 initial evaluation and $75 follow-up visits are billed separately from medication
- Filled through your 'preferred pharmacy' — no single named compounding pharmacy partner
- No LegitScript certification displayed
Our Verdict
NewSelf edges out Wholesome Clinic with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Wholesome Clinic remains a solid alternative, especially if you're looking for Multi-state telehealth pairing compounded GLP-1 weight loss with integrative psychiatry.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Choose Wholesome Clinic if…
You want Multi-state telehealth pairing compounded GLP-1 weight loss with integrative psychiatry and a starting price around $109/mo.
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Maximus
Men seeking compounded GLP-1 alongside testosterone optimization
From $199.99/mo
Get started →Sesame Care
Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding
From $25/mo
Get started →MEDVi
Patients who want the option to switch between compounded and brand-name GLP-1 through one provider
From $99/mo
Get started →NewSelf vs Wholesome Clinic: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.