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NewSelf vs Tyde Wellness

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf
VS
Tyde Wellness logo

Tyde Wellness

8.0
★★★★4/5

Best for: compounded GLP-1 with five named LegitScript-certified pharmacy partners

Visit Tyde Wellness

NewSelf and Tyde Wellness are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $119/mo, and NewSelf edges ahead overall (8.3 vs 8.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

Tyde Wellness

All doses (microdose + full-strength)Compounded
$149/mo
semaglutide
All doses (microdose + full-strength)Compounded
$249/mo
tirzepatide
Oral tablet (low-dose)Compounded
$119/mo
naltrexone

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What’s included

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Tyde Wellness

What the monthly price covers

Medication

Not disclosed

Provider visits

Included

Shipping

Not disclosed

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

NewSelf

8.3/10

Overall

Tyde Wellness

8.0/10

Value25%

9.0A
vs
B
8.0

Effectiveness25%

8.0A
vs
B
8.0

User Experience15%

8.0A
vs
B
7.5

Trust & Safety15%

8.3A
vs
B
8.3

Accessibility10%

8.5A
vs
B
8.0

Support10%

7.9A
vs
B
7.9

Features & Coverage

FeatureNewSelfTyde Wellness
Starting Price$100/mo$119/mo
Features6 features8 features
States Available4950
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

About Tyde Wellness

Tyde Wellness is a 50-state compounded-GLP-1 and longevity telehealth platform spanning weight loss, HRT, hair, and peptides. Its standout is supply-chain transparency — five named, LegitScript-certified 503A compounding pharmacy partners — plus a free consultation and a cancel-anytime subscription. Compounded semaglutide starts at $149/mo, tirzepatide at $249/mo, and low-dose naltrexone from $119/mo.

Read our full Tyde Wellness review →

Pros & Cons

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Tyde Wellness

What we like

  • All 50 states served (full list published)
  • Transparent pricing: semaglutide from $149/mo, tirzepatide from $249/mo
  • LegitScript Certified with a verification link
  • Five named 503A pharmacy partners with addresses: Belmar (CO), Casa (TX), Olympia (FL), Red Rock (UT), Beaker (TX)
  • Free consultation; cancel-anytime subscription with no long-term commitment
  • Microdose and full-strength options for both GLP-1s
  • Single account covers weight loss, HRT, hair, and longevity peptides

Watch-outs

  • Compounded semaglutide and tirzepatide are not FDA-approved finished products
  • No brand-name GLP-1s (Wegovy, Zepbound, Mounjaro, Ozempic)
  • Tirzepatide priced higher than competitors offering $200-$249/mo
  • Corporate address and medical director not publicly disclosed
  • No NABP .pharmacy seal visible

Our Verdict

Winner: NewSelf

NewSelf edges out Tyde Wellness with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Tyde Wellness remains a solid alternative, especially if you're looking for compounded GLP-1 with five named LegitScript-certified pharmacy partners.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

Choose Tyde Wellness if…

You want compounded GLP-1 with five named LegitScript-certified pharmacy partners and a starting price around $119/mo.

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NewSelf vs Tyde Wellness: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.