NewSelf vs tru Weight Loss
An in-depth comparison of two leading GLP-1 Providers
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NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →tru Weight Loss
Best for: patients wanting all-inclusive md-directed glp-1 care with labs and coaching
Visit tru Weight Loss →NewSelf and tru Weight Loss are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $299/mo, and NewSelf edges ahead overall (8.3 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
NewSelf
All dosages same price
All dosages same price
tru Weight Loss
3-month minimum then cancel anytime; includes consult, labs, coaching, and delivery
3-month minimum then cancel anytime; includes consult, labs, coaching, and delivery
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What’s included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
tru Weight Loss
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.3/10
tru Weight Loss
6.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | NewSelf | tru Weight Loss |
|---|---|---|
| Starting Price | ✓$100/mo | $299/mo |
| Features | 6 features | 6 features |
| States Available | 49 | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →About tru Weight Loss
tru Weight Loss (truhealthnow) is a physician-directed telehealth program prescribing compounded semaglutide and tirzepatide, shipped from US-licensed compounding pharmacies. Pricing is flat: semaglutide 299 dollars per month and tirzepatide 399 per month, with a 3-month minimum then cancel anytime. The fee bundles the telehealth consult, lab work, a personalized plan, medication delivery, and nutritionist and behavioral coaching. Directed by Neha Grover, MD, from a clinic in Germantown, Maryland. Insurance, HSA, and FSA are not accepted.
Read our full tru Weight Loss review →Pros & Cons
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
tru Weight Loss
What we like
- Flat, transparent pricing (299/mo semaglutide, 399/mo tirzepatide)
- All-inclusive: consult, lab work, medication delivery, nutritionist and behavioral coaching
- Directed by a named physician (Neha Grover, MD) from a physical clinic
Watch-outs
- Requires a 3-month commitment before you can cancel
- States served are not specified and the dispensing pharmacy is not named
- Does not accept insurance, HSA, or FSA
Our Verdict
NewSelf edges out tru Weight Loss with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. tru Weight Loss remains a solid alternative, especially if you're looking for patients wanting all-inclusive md-directed glp-1 care with labs and coaching.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Choose tru Weight Loss if…
You want patients wanting all-inclusive md-directed glp-1 care with labs and coaching and a starting price around $299/mo.
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Maximus
Men seeking compounded GLP-1 alongside testosterone optimization
From $199.99/mo
Get started →Sesame Care
Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding
From $25/mo
Get started →Try Ageless
Lowest-tier compounded GLP-1 in injection, troche and sublingual forms
From $119/mo
Get started →NewSelf vs tru Weight Loss: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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