NewSelf vs SynergenX Health
An in-depth comparison of two leading GLP-1 Providers
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NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →
SynergenX Health
Best for: TX patients wanting clinic-backed GLP-1; sema from $150/mo, all-in
Visit SynergenX Health →NewSelf and SynergenX Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $150/mo, and NewSelf edges ahead overall (8.3 vs 6.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
NewSelf
All dosages same price
All dosages same price
SynergenX Health
Verbatim: 'Medication starts as low as $150 for one month of treatment' (compounded semaglutide). Includes medication per site ('SynergenX covers the full cost of your medication'). Initial telehealth consult $100 and follow-up visits $40/visit every 1–3 months billed separately. Dose-escalation tiers not disclosed.
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What’s included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
SynergenX Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Billed separately
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.3/10
SynergenX Health
6.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | NewSelf | SynergenX Health |
|---|---|---|
| Starting Price | ✓$100/mo | $150/mo |
| Features | 6 features | ✓8 features |
| States Available | ✓49 | 10 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | 1 warning | ✓None |
About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →About SynergenX Health
SynergenX Health is a multi-state hormone and weight-loss clinic chain with 64 locations across 10 states offering a telehealth GLP-1 program currently available to Texas patients. The online program provides compounded semaglutide starting at $150/month with medication and refrigerated home shipping included after a $100 initial telehealth consultation. Follow-up visits run $40 every 1–3 months; treatment includes personalized dosing, ongoing clinical support, and lifestyle and nutrition counseling.
Read our full SynergenX Health review →Pros & Cons
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
SynergenX Health
What we like
- Compounded semaglutide from $150/mo including medication and refrigerated home shipping — no hidden fees stated on site
- Backed by 64-clinic chain operating across 10 states with medical providers for in-person or telehealth care
- Telehealth consultations from home; $100 initial visit, $40 follow-up every 1–3 months
- Nutrition counseling and lifestyle planning included as part of personalized treatment program
- Free weight-loss consultation option available before committing to paid evaluation
Watch-outs
- Telehealth GLP-1 program currently Texas-only; rolling out more states but no timeline published
- Tirzepatide not confirmed for online program; only compounded semaglutide explicitly listed
- Labs not included or mentioned; no baseline bloodwork protocol disclosed on website
- Dose-escalation pricing not published; $150/mo is entry dose only, higher doses may cost more
- No LegitScript, named medical director, or publicly disclosed compounding pharmacy partner found
Our Verdict
NewSelf edges out SynergenX Health with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. SynergenX Health remains a solid alternative, especially if you're looking for TX patients wanting clinic-backed GLP-1; sema from $150/mo, all-in.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Choose SynergenX Health if…
You want TX patients wanting clinic-backed GLP-1; sema from $150/mo, all-in and a starting price around $150/mo.
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GobyMeds
Budget-conscious shoppers
From $93/mo
Get started →Direct Meds
Listed for disclosure only — see its FDA warning and BBB complaints first
From $249/mo
Get started →Maximus
Men seeking compounded GLP-1 alongside testosterone optimization
From $199.99/mo
Get started →NewSelf vs SynergenX Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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