NewSelf vs Southern Vitality and Weight Loss
An in-depth comparison of two leading GLP-1 Providers
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NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →
Southern Vitality and Weight Loss
Best for: cheap compounded GLP-1 from a provider that names its pharmacies
Visit Southern Vitality and Weight Loss →NewSelf and Southern Vitality and Weight Loss are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Southern Vitality and Weight Loss starts lower at $99/mo versus $100/mo, and NewSelf edges ahead overall (8.3 vs 7.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
NewSelf
All dosages same price
All dosages same price
Southern Vitality and Weight Loss
"GLP-1 starting as low as $99/mo"; flexible financing available
"GLP-1 starting as low as $99/mo"; flexible financing available
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What’s included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Southern Vitality and Weight Loss
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.3/10
Southern Vitality and Weight Loss
7.8/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | NewSelf | Southern Vitality and Weight Loss |
|---|---|---|
| Starting Price | $100/mo | ✓$99/mo |
| Features | 6 features | ✓8 features |
| States Available | 49 | Not disclosed |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →About Southern Vitality and Weight Loss
Southern Vitality and Weight Loss is a physician-supervised telehealth weight-loss program (operating since 2012) offering compounded semaglutide and tirzepatide starting as low as $99/mo, plus vitamin injections and peptides. It includes a free telehealth consult, free shipping, and bi-weekly check-ins, with no membership or hidden fees. Unusually, it names its compounding pharmacy partners — PerfectRx, The Pharmacy Hub, and RX Compound Store. The company is Georgia-based and does not publish its state-availability list.
Read our full Southern Vitality and Weight Loss review →Pros & Cons
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Southern Vitality and Weight Loss
What we like
- Compounded GLP-1 (semaglutide and tirzepatide) starting as low as $99/mo
- Names its compounding pharmacy partners (PerfectRx, The Pharmacy Hub, RX Compound Store) — uncommon transparency
- Free telehealth consult and free shipping; no membership or hidden fees
- Bi-weekly check-ins; operating since 2012
- Flexible monthly financing available at checkout
Watch-outs
- All sales final once a prescription is approved and sent to the pharmacy
- States of operation not published
- Not LegitScript-certified (no certification displayed)
- Prescribing medical group not named (only "licensed providers")
Our Verdict
NewSelf edges out Southern Vitality and Weight Loss with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Southern Vitality and Weight Loss remains a solid alternative, especially if you're looking for cheap compounded GLP-1 from a provider that names its pharmacies.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Choose Southern Vitality and Weight Loss if…
You want cheap compounded GLP-1 from a provider that names its pharmacies and a starting price around $99/mo.
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Maximus
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From $199.99/mo
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Brand-name GLP-1s at cash prices, no compounding
From $25/mo
Get started →Try Ageless
Lowest-tier compounded GLP-1 in injection, troche and sublingual forms
From $119/mo
Get started →NewSelf vs Southern Vitality and Weight Loss: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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