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NewSelf vs Semaglutide Online

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf
VS
Semaglutide Online logo

Semaglutide Online

7.5
★★★3.8/5

Best for: LegitScript GLP-1 nationwide ex. AL; sema $199 or tirz $299/mo all-in

Visit Semaglutide Online

NewSelf and Semaglutide Online are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $199/mo, and NewSelf edges ahead overall (8.3 vs 7.5 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

Semaglutide Online

All dosesCompounded
$199/mo
semaglutide

Verbatim: '$199/month all-inclusive' (compounded semaglutide, oral or injectable). Includes medication, supplies, delivery, and provider care. Brand injectable semaglutide (Wegovy/Ozempic) is $199/month medication + $44/month provider fee = $243/month total; brand oral semaglutide (Wegovy pill) is $149/month + $44/month = $193/month total. Financing available via Credee from $79/month at 0% interest (12-24 months).

All dosesCompounded
$299/mo
tirzepatide

Verbatim: '$299/month all-inclusive' (compounded tirzepatide, oral or injectable). Includes medication, supplies, delivery, and provider care. Brand injectable tirzepatide (Zepbound) is $299/month medication + $44/month provider fee = $343/month total. Financing available via Credee from $79/month at 0% interest (12-24 months).

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What’s included

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Semaglutide Online

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Billed separately

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

NewSelf

8.3/10

Overall

Semaglutide Online

7.5/10

Value25%

9.0A
vs
B
7.5

Effectiveness25%

8.0A
vs
B
7.0

User Experience15%

8.0A
vs
B
7.5

Trust & Safety15%

8.3A
vs
B
7.8

Accessibility10%

8.5A
vs
B
9.0

Support10%

7.9A
vs
B
6.9

Features & Coverage

FeatureNewSelfSemaglutide Online
Starting Price$100/mo$199/mo
Features6 features8 features
States Available4950
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA Warnings1 warningNone

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

About Semaglutide Online

Semaglutide Online is a LegitScript-certified telehealth platform prescribing compounded and brand-name GLP-1/GIP medications nationwide (excluding Alabama). Compounded semaglutide and tirzepatide are priced at $199 and $299 per month all-inclusive, while brand-name options (Wegovy, Ozempic, Zepbound) add a $44/month provider-care fee on top of medication cost. A free asynchronous health intake is reviewed by a licensed provider within 12 hours; no appointment is required. Financing via Credee, Affirm, and Klarna starts as low as $79/month at 0% interest.

Read our full Semaglutide Online review →

Pros & Cons

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Semaglutide Online

What we like

  • LegitScript certified — passes accreditation standards recognized by Google and Visa for online telehealth
  • Compounded all-in pricing: semaglutide $199/mo and tirzepatide $299/mo includes medication, provider care, and shipping
  • Brand-name options (Wegovy pill, injectable sema, Zepbound) available for eligible patients, potentially $0-$25/mo with insurance
  • Nationwide (49 states + DC); no appointment required, licensed provider reviews intake within 12 hours
  • 0% financing through Credee from $79/month (12-24 months) plus Affirm and Klarna with ~97% approval rate

Watch-outs

  • No labs or clinical monitoring disclosed — blood work requirements not mentioned anywhere on site
  • Leadership team and medical director not identified on site — no named prescribers or company founders published
  • Brand-name prescriptions add a $44/month provider fee on top of medication cost, raising total price to $193-$343/mo
  • No coaching, dietitian, or behavioral support at any tier — medication and async provider access only
  • 30-day satisfaction guarantee covers evaluation fee only; medication costs explicitly non-refundable

Our Verdict

Winner: NewSelf

NewSelf edges out Semaglutide Online with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Semaglutide Online remains a solid alternative, especially if you're looking for LegitScript GLP-1 nationwide ex. AL; sema $199 or tirz $299/mo all-in.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

Choose Semaglutide Online if…

You want LegitScript GLP-1 nationwide ex. AL; sema $199 or tirz $299/mo all-in and a starting price around $199/mo.

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7.3

Sunlight

Compounded GLP-1 with unlimited telehealth visits and free shipping

7.4

MadeMed

Compounded GLP-1 in both injection and oral forms

8.3

Found

Mainstream telehealth GLP-1 access

NewSelf vs Semaglutide Online: FAQ

Key terms, explained

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.