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NewSelf vs Pepti

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf
VS
Pepti logo

Pepti

7.9
★★★★4/5

Best for: the lowest all-in monthly price we have verified on compounded semaglutide, labs included

Visit Pepti

NewSelf and Pepti are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Pepti starts lower at $99/mo versus $100/mo, and NewSelf edges ahead overall (8.3 vs 7.9 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

Pepti

Injectable, flat all-in price at every titration doseCompounded
$99/mo
semaglutide

All-in monthly subscription covering medication, physician care, labs and shipping. A one-time non-subscription vial is $124.

Injectable, flat all-in price at every titration doseCompounded
$199/mo
tirzepatide

All-in monthly subscription. A one-time non-subscription vial is $249.

Oral formulation, no needlesCompounded
$249/mo
semaglutide

Oral semaglutide, priced above the injectable.

Oral formulation, no needlesCompounded
$399/mo
tirzepatide

Oral tirzepatide, priced above the injectable.

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What’s included

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Pepti

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Included

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

NewSelf

8.3/10

Overall

Pepti

7.9/10

Value25%

9.0A
vs
B
9.0

Effectiveness25%

8.0A
vs
B
7.5

User Experience15%

8.0A
vs
B
8.5

Trust & Safety15%

8.3A
vs
B
7.0

Accessibility10%

8.5A
vs
B
7.0

Support10%

7.9A
vs
B
7.5

Features & Coverage

FeatureNewSelfPepti
Starting Price$100/mo$99/mo
Features6 features7 features
States Available4936
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

About Pepti

Pepti is a Delaware-registered telehealth platform selling doctor-prescribed compounded peptides and GLP-1s across 36 states. Injectable semaglutide is $99 a month all-in and tirzepatide $199, each covering medication, physician review, baseline labs, refill management and shipping in a single flat price that does not rise with dose. The catalogue runs to more than 120 products across weight loss, hormones and TRT, recovery, cognitive and skin categories, plus at-home bloodwork. Pepti is a platform, not a prescriber, and does not bill insurance.

Read our full Pepti review →

Pros & Cons

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Pepti

What we like

  • At $99/mo all-in, injectable semaglutide is among the cheapest verified prices in our catalogue.
  • States plainly that all doses cost one flat monthly price, so titrating up never raises the bill.
  • Publishes a page for each of the 36 states it serves, and the page count matches its claim exactly.
  • Names the reviewing physician, Dr. Gene Lee MD, and discloses pepti LLC as the Delaware operating entity.

Watch-outs

  • The homepage shows an "FDA Cleared" badge beside peptide therapy, though product pages correctly say compounded drugs are not FDA-approved.
  • Neither the 503A nor the 503B compounding pharmacy is named, so you cannot check who dispenses.
  • The listed address, a Newark Delaware suite, is a shared registered-agent address rather than a clinical office.
  • Cash-pay only with no insurance billing, and the oral formulations jump to $249 and $399 a month.

Our Verdict

Winner: NewSelf

NewSelf edges out Pepti with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Pepti remains a solid alternative, especially if you're looking for the lowest all-in monthly price we have verified on compounded semaglutide, labs included.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

Choose Pepti if…

You want the lowest all-in monthly price we have verified on compounded semaglutide, labs included and a starting price around $99/mo.

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7.6

Sprout Health

LegitScript-verified compounded GLP-1 via named pharmacies

7.5

PeterMD

Men wanting flat-priced compounded GLP-1 with TRT or peptides

7.8

Care Bare Rx

LGBTQ+-inclusive compounded GLP-1 telehealth

NewSelf vs Pepti: FAQ

Key terms, explained

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