MDExam vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →MDExam and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $225/mo, and NewSelf edges ahead overall (8.3 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
MDExam
⛔ MDEXAM PUBLISHES TWO DIFFERENT PRICES FOR THIS SAME PRODUCT. /injectable-semaglutide renders 'Semaglutide Weight Loss Program | Price | $192' with NO billing period stated anywhere, while /medications/injectable-semaglutide renders 'Price | $225' for the identical product. We record $225 because it is the ONLY figure the site ever attaches to a period: 'Our program is priced as low as $225 per month, which includes telemedicine visits, nutrition and exercise coaching, and medication.' Treat $192 as an unlabelled promotional figure until a checkout can be walked — /checkout renders an empty body without a session.
'Injectable Tirzepatide Program | Price | $258'. ⚠ NO BILLING PERIOD IS STATED ON THIS CARD EITHER. It is recorded as monthly on the strength of the site-wide FAQ, which frames the whole program as 'as low as $225 per month ... includes telemedicine visits, nutrition and exercise coaching, and medication' — $258 sits above that floor, consistent with a monthly tirzepatide rate. That is an inference from the program framing, not a quoted period, and it should be re-checked at checkout.
NewSelf
All dosages same price
All dosages same price
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What’s included
MDExam
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Not disclosed
Lab work
Not disclosed
Coaching
Included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
MDExam
7.1/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | MDExam | NewSelf |
|---|---|---|
| Starting Price | $225/mo | ✓$100/mo |
| Features | 2 features | ✓6 features |
| States Available | Not disclosed | 49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | ✓None | 1 warning |
About MDExam
Telehealth provider whose GLP-1 program bundles telemedicine visits, nutrition and exercise coaching and the medication into one price — stated as as low as $225 per month for semaglutide and $258 for tirzepatide. Note the site publishes a second, lower figure for semaglutide on a different page without saying what period it covers.
Read our full MDExam review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
MDExam
What we like
- Both semaglutide and tirzepatide available
Watch-outs
- Pricing not publicly disclosed
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out MDExam with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. MDExam remains a solid alternative, especially if you're looking for mainstream telehealth GLP-1 access.
Choose MDExam if…
You want mainstream telehealth GLP-1 access and a starting price around $225/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Ready to start? Vetted GLP-1 providers
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Strut Health
Oral-lozenge compounded GLP-1 access
From $99/mo
Get started →Yucca Health
Mainstream telehealth GLP-1 access
From $146/mo
Get started →TrimRx
Best overall value
From $149/mo
Get started →MDExam vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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