MD Trim Clinic vs Enhance MD
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
MD Trim Clinic
Best for: DO+NP-led compounded sema/tirz clinic; tiered dosing, AZ+CA telehealth + in-office, B12 anti-nausea
Visit MD Trim Clinic →
Enhance MD
Best for: lab-monitored compounded GLP-1 with mandatory video visit
Visit Enhance MD →MD Trim Clinic and Enhance MD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Enhance MD starts at $212/mo, and Enhance MD edges ahead overall (8.6 vs 5.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
MD Trim Clinic
Pricing not publicly listed.
Enhance MD
What’s included
MD Trim Clinic
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Billed separately
Enhance MD
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Not disclosed
Lab work
Included
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
MD Trim Clinic
5.8/10
Enhance MD
8.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | MD Trim Clinic | Enhance MD |
|---|---|---|
| Starting Price | — | $212/mo |
| Features | ✓8 features | 6 features |
| States Available | 2 | ✓39 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About MD Trim Clinic
MD Trim Clinic is a small physician-led practice in Phoenix, AZ and Novato, CA offering compounded semaglutide and tirzepatide via telehealth and in-person visits. Medications are dispensed from LegitScript-certified pharmacies with B12 added to reduce nausea, and programs are tiered by weekly dose (Level 1 / Level 2). Led by Dr. Brandon Shaw, D.O. and nurse practitioner Andrea Farris, N.P., the clinic includes free initial screening, physician-guided dosing titration, and ongoing team support.
Read our full MD Trim Clinic review →About Enhance MD
Enhance MD pairs compounded semaglutide and tirzepatide with mandatory baseline metabolic labs at Quest Diagnostics and a synchronous video visit with a board-certified clinician — a more rigorous onboarding than the async-only compounded GLP-1 model most telehealth providers use. Three tiers (Core semaglutide, Advanced tirzepatide, Elite combined) plus aggressive intro pricing ($49 first month on Core).
Read our full Enhance MD review →Pros & Cons
MD Trim Clinic
What we like
- Physician DO + NP team (Dr. Brandon Shaw, D.O. and Andrea Farris, N.P.) provides strong clinical oversight
- Compounded meds from LegitScript-certified pharmacies — higher supply-chain trust than many small practices
- Tiered dosing structure (Level 1 / Level 2) with B12 added to reduce nausea side effects
- Both telehealth and in-person options available (AZ Phoenix and CA Novato offices)
- Partnered mobile IV services available for enhanced nausea management and hydration support
Watch-outs
- Pricing not disclosed publicly — must contact clinic for quotes, limiting upfront comparison shopping
- Only AZ and CA confirmed — very limited geographic reach, excludes nearly all of the US
- No LegitScript certification for the clinic itself (only pharmacy partners are LegitScript-certified)
- Small practice with limited online presence and no published patient reviews or outcomes data
- No labs, coaching, or monitoring protocols disclosed on the site
Enhance MD
What we like
- Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
- Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
- Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
- Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
- Low first-month intro pricing: $49 Core, $99 Advanced, $189 Elite
- Unlimited clinician messaging and dose-adjustment support included
Watch-outs
- Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
- Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
- No insurance accepted — cash pay, HSA/FSA eligible
- Intro pricing resets to full tier rate after 30 days — the $49/$99/$189 figures aren't ongoing cost
Our Verdict
Enhance MD edges out MD Trim Clinic with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. MD Trim Clinic remains a solid alternative, especially if you're looking for DO+NP-led compounded sema/tirz clinic; tiered dosing, AZ+CA telehealth + in-office, B12 anti-nausea.
Choose MD Trim Clinic if…
You want DO+NP-led compounded sema/tirz clinic; tiered dosing, AZ+CA telehealth + in-office, B12 anti-nausea.
Choose Enhance MD if…
You want lab-monitored compounded GLP-1 with mandatory video visit and a starting price around $212/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online, ranked by our editorial score.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Bodybuilding Health+
Fitness-brand compounded GLP-1 with hormone and performance programs
From $179/mo
Get started →Gala
Compounded GLP-1/GIP combo therapy on a yearly subscription with free shipping nationwide
From $149/mo
Get started →Trimi Health
Budget-conscious shoppers
From $99/mo
Get started →MD Trim Clinic vs Enhance MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring MD Trim Clinic and Enhance MD head-to-heads in the same category.
- MD Trim Clinic vs CoreAge Rx
- MD Trim Clinic vs Amazon One Medical
- MD Trim Clinic vs NovoCare Pharmacy
- Enhance MD vs Vytora Health
- Enhance MD vs Noom Med
- Enhance MD vs Novi
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.