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Loop Health vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Loop Health logo

Loop Health

6.9
★★★3.5/5

Best for: peptide and wellness membership with GLP-1s as one offering

Visit Loop Health
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

Loop Health and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Loop Health starts lower at $79/mo versus $100/mo, and NewSelf edges ahead overall (8.3 vs 6.9 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Loop Health

Membership (monthly)Compounded
$79/mo
semaglutide
Membership (annual, includes $180/mo research credit)Compounded
$125/mo
tirzepatide

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

Loop Health

Inclusions not disclosed.

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Loop Health

6.9/10

Overall

NewSelf

8.3/10

Value25%

6.5A
vs
B
9.0

Effectiveness25%

7.0A
vs
B
8.0

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

6.8A
vs
B
8.3

Accessibility10%

7.0A
vs
B
8.5

Support10%

7.4A
vs
B
7.9

Features & Coverage

FeatureLoop HealthNewSelf
Starting Price$79/mo$100/mo
Features6 features6 features
States AvailableNot disclosed49
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About Loop Health

Loop Health is a US telehealth membership platform offering compounded semaglutide and tirzepatide under its Loop Lean program, alongside peptides, NAD+, sermorelin, coaching, and bloodwork. It connects members to independent licensed providers rather than prescribing directly. Membership starts at $79/month, or $1,500/year with a $180/month research credit toward compounds; per-drug pricing is billed separately by the pharmacy.

Read our full Loop Health review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

Loop Health

What we like

  • Multi-product wellness platform — GLP-1 plus peptides, NAD+, coaching, bloodwork
  • Low membership entry point ($79/mo)
  • Annual plan includes monthly 'research credit' toward compounds
  • Explicit compounded-drug FDA disclaimer on-site

Watch-outs

  • Per-dose GLP-1 drug pricing not transparent on public site (compounds billed separately by pharmacy)
  • States-served list not enumerated — only 'select U.S. states'
  • Platform explicitly 'is not a healthcare provider' — relies on independent provider network
  • No LegitScript number disclosed on homepage

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out Loop Health with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Loop Health remains a solid alternative, especially if you're looking for peptide and wellness membership with GLP-1s as one offering.

Choose Loop Health if…

You want peptide and wellness membership with GLP-1s as one offering and a starting price around $79/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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Loop Health vs NewSelf: FAQ

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