Leland Health vs Vytora Health
In our scoring, Vytora Health edges ahead overall (8.4 vs 6.8 out of 10), and Leland Health costs less for compounded semaglutide (about $471 a year less; one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost).
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Key differences
- Price
- Leland Health $129/mo vs Vytora Health $179/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $471 a year less with Leland Health · one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Coverage
- Vytora Health 50 states + DC (Leland Health doesn't publish a state list)
- Included
- Leland Health: not stated; Vytora Health: medication, clinician visits, shipping

Leland Health
Best for compounded semaglutide or tirzepatide with starting prices shown upfront and no prepay, billed every 4 weeks
semaglutide
$129
billed every 4 weeks
Our score 6.8/10

Vytora Health
Best for compounded or brand-name GLP-1 with named pharmacy partners, 50 states
semaglutide
$179
Our score 8.4/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Leland Health
Vytora Health
Price
Semaglutide / month
Better on this row: $129/mo
billed every 4 weeks
$179/mo
Semaglutide / year (modeled)
Better on this row: $1,677
13 charges
$2,148
Tirzepatide / month
Better on this row: $149/mo
billed every 4 weeks
$249/mo
Tirzepatide / year (modeled)
Better on this row: $1,937
13 charges
$2,988
Oral semaglutide / month
$179/mo
billed every 4 weeks
Not listed
Brand Zepbound / Mounjaro / month
Not listed
$1,399/mo
Coverage
State availability
List not published
50 states + DC
Oral option listed
Yes
Not listed
Brand-name access listed
Not listed
Zepbound / Mounjaro
Included in the price
Not disclosed
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
Yes
Yes
Minimum commitment
None stated; plans renew every 4 weeks until you cancel
None on monthly plans; 3-month plans are billed every 3 months
Refunds
Full refund if medically disqualified, or if canceled within the first 72 hours before any services are received; otherwise no refund on cancellation, and shipped medication is not refundable
'All sales are final' for prescription products; refund requests 'reviewed on a case-by-case basis'
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
October 2026
Every dose and plan: Leland Health · Vytora Health
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.

Choose Leland Health if…
- About $471 a year less than Vytora Health for compounded semaglutide at standing prices (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Lists oral compounded semaglutide, which Vytora Health doesn't price
- Names its clinical network, OpenLoop Health, and four dispensing pharmacies with addresses in its terms
What to weigh up
- No published state list; confirm yours at signup
- Every price is a 'starting' price billed every 4 weeks, so a year is 13 charges, and dose-based pricing is not published

Choose Vytora Health if…
- Lists brand-name Zepbound / Mounjaro, which Leland Health doesn't price
- Publishes its full state list (50 states + DC)
- Both compounded and brand-name options on one platform
What to weigh up
- About $471 a year more than Leland Health for compounded semaglutide (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Brand-name Mounjaro and Zepbound at $1,399/mo are priced at retail; manufacturer self-pay programs are often cheaper
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Leland Health
6.8/10
Vytora Health
8.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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From $139/mo
Get started →From $299/mo
Get started →SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →Leland Health vs Vytora Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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