HealthRX vs Lttl
In our scoring, HealthRX edges ahead overall (7.3 vs 7.2 out of 10), and Lttl costs less for compounded semaglutide (about $693 a year less; one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost).
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Key differences
- Price
- Lttl $99/mo vs HealthRX $165/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $693 a year less with Lttl · one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Included
- HealthRX: medication, clinician visits, shipping; Lttl: medication, clinician visits, shipping
HealthRX
Affiliate partnerBest for flat-price compounded GLP-1, LegitScript-certified cash-pay program
semaglutide
$165
Our score 7.3/10

Lttl
Affiliate partnerBest for every commitment tier priced openly, plus a low-dose microdose option
semaglutide
$99
billed every 4 weeks
Our score 7.2/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
HealthRX
Lttl
Price
Semaglutide / month
$165/mo
Better on this row: $99/mo
billed every 4 weeks
Semaglutide / year (modeled)
$1,980
Better on this row: $1,287
13 charges
Tirzepatide / month
$214/mo
Better on this row: $149/mo
billed every 4 weeks
Tirzepatide / year (modeled)
$2,568
Better on this row: $1,937
13 charges
Oral semaglutide / month
Not listed
$179/mo
$149 first month
Coverage
Oral option listed
Not listed
Yes
Included in the price
Medication, clinician visits, shipping
Medication, clinician visits, shipping
FSA/HSA accepted
Yes
Yes
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
Yes
Yes
Minimum commitment
None
None on the monthly plan; 3-, 6- and 12-month prepay tiers offered at lower per-month rates
Refunds
Refund if not approved; unshipped doses refunded
Not disclosed
Early-cancellation fee
None
Not disclosed
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
October 2026
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose HealthRX if…
- LegitScript-certified (certificate 50087439) and posts the FDA compounded disclaimer — real trust signals for a compounded-GLP-1 program
- Free overnight cold shipping, no insurance needed, HSA/FSA eligible, and a full refund if a clinician doesn't approve you
- One-click cancellation and a refund on any unshipped dose — no phone-call retention wall
What to weigh up
- About $693 a year more than Lttl for compounded semaglutide (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Doesn't publicly name its 503A compounding pharmacy — you can't check that part of the supply chain yourself

Choose Lttl if…
- About $693 a year less than HealthRX for compounded semaglutide at standing prices (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Lists oral compounded semaglutide, which HealthRX doesn't price
- Publishes the full price matrix — every medication, form and commitment length — on a public /plans page before checkout
What to weigh up
- Partner pharmacies are never named — the site refers only to 'a partner U.S. pharmacy' (a material disclosure gap for a YMYL purchase)
- Headline 'Plans start at' prices ($89 semaglutide, $139 tirzepatide) are 12-month prepay rates; month-to-month is $99 and $149
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
HealthRX
7.3/10
Lttl
7.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →From $219/mo
Get started →HealthRX vs Lttl: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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