Always verify pricing and state availability on the provider's website before signing up.How our reviews work →

Defy Medical vs CoreAge Rx

An in-depth comparison of two leading GLP-1 Providers

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Defy Medical logo

Defy Medical

7.0
★★★3.5/5

Best for: Patients wanting GLP-1 in injection, ODT, or drop forms with thorough lab workups

Visit Defy Medical
VS
CoreAge Rx logo

CoreAge Rx

8.3
★★★★4.2/5

Best for: best overall value

Visit CoreAge Rx

Defy Medical and CoreAge Rx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, CoreAge Rx starts at $149/mo, and CoreAge Rx edges ahead overall (8.3 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Defy Medical

Pricing not publicly listed.

CoreAge Rx

0.25mgCompounded
$149/mo
semaglutide
0.5mgCompounded
$199/mo
semaglutide
1mgCompounded
$249/mo
semaglutide
1.7mgCompounded
$299/mo
semaglutide
2.5mgCompounded
$349/mo
tirzepatide

Get alerted when GLP-1 prices drop

Join the GLP-1 price-watch list — we re-verify 390+ providers' prices on their own sites and email you when tracked prices move.

What’s included

Defy Medical

Inclusions not disclosed.

CoreAge Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Defy Medical

7.0/10

Overall

CoreAge Rx

8.3/10

Value25%

6.5A
vs
B
8.5

Effectiveness25%

7.5A
vs
B
8.5

User Experience15%

6.5A
vs
B
8.5

Trust & Safety15%

7.0A
vs
B
7.8

Accessibility10%

7.0A
vs
B
8.0

Support10%

7.4A
vs
B
8.4

Features & Coverage

FeatureDefy MedicalCoreAge Rx
Starting Price$149/mo
Features8 features6 features
States AvailableNot disclosed50
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About Defy Medical

Defy Medical is a long-running telehealth clinic, best known for hormone replacement, that also prescribes GLP-1 medications for weight loss. It offers semaglutide and tirzepatide as weekly injections plus oral disintegrating tablets (ODT) and liquid drops, and liraglutide as a daily injection. The drops and ODT forms help patients avoid self-injecting or get treatment where injectable shipping is restricted. Care includes in-depth consults and comprehensive blood testing, with mobile phlebotomy. Medical director is Dr. Justin Saya. GLP-1 pricing and state coverage are not published online.

Read our full Defy Medical review →

About CoreAge Rx

CoreAge Rx offers LegitScript-verified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.

Read our full CoreAge Rx review →

Pros & Cons

Defy Medical

What we like

  • Multiple GLP-1 options: semaglutide, tirzepatide, liraglutide
  • Offers injection, ODT, and oral drop delivery forms
  • Comprehensive blood testing and named medical director
  • Established clinic with strong Trustpilot review volume

Watch-outs

  • GLP-1 pricing not published on the website
  • States served and shipping limits not disclosed
  • Compounded versus brand status not stated online
  • Lab-heavy, consult-first model may cost more upfront

CoreAge Rx

What we like

  • LegitScript certified — rigorous pharmacy standards
  • Free 2-day shipping nationwide
  • Both semaglutide and tirzepatide available
  • Lowest per-month pricing in the compounded segment
  • 24/7 support team
  • All 50 states covered

Watch-outs

  • Compounded only — no brand-name Ozempic or Wegovy
  • Newer brand with fewer independent reviews than legacy players

Our Verdict

Winner: CoreAge Rx

CoreAge Rx edges out Defy Medical with a higher overall score of 8.3/10 and is particularly strong for best overall value. Defy Medical remains a solid alternative, especially if you're looking for Patients wanting GLP-1 in injection, ODT, or drop forms with thorough lab workups.

Choose Defy Medical if…

You want Patients wanting GLP-1 in injection, ODT, or drop forms with thorough lab workups.

Choose CoreAge Rx if…

You want best overall value and a starting price around $149/mo.

Ready to start? Vetted GLP-1 providers

Vetted telehealth providers that prescribe GLP-1 online.

No insurance needed · vetted by our editors

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

6.9

DudeMeds

Men seeking no-fee GLP-1 access with oral and injectable options

7.8

Yucca Health

Mainstream telehealth GLP-1 access

7.7

TrimRx

Best overall value

Defy Medical vs CoreAge Rx: FAQ

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring Defy Medical and CoreAge Rx head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.