Defy Medical vs CoreAge Rx
An in-depth comparison of two leading GLP-1 Providers
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Defy Medical
Best for: GLP-1 in injection, ODT, or drop forms with thorough lab workups
Visit Defy Medical →
Defy Medical and CoreAge Rx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, CoreAge Rx starts at $99/mo, and CoreAge Rx edges ahead overall (8.3 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Defy Medical
Pricing not publicly listed.
CoreAge Rx
Re-verified 2026-08-05: homepage + Preventive Longevity section both show "Semaglutide — Starting at $99/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.
Re-verified 2026-08-05: homepage GLP-1 hero + Preventive Longevity section both show "Tirzepatide — Starting at $149/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.
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What’s included
Defy Medical
Inclusions not disclosed.
CoreAge Rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Defy Medical
7.0/10
CoreAge Rx
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Defy Medical | CoreAge Rx |
|---|---|---|
| Starting Price | — | $99/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 50 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Defy Medical
Defy Medical is a long-running telehealth clinic, best known for hormone replacement, that also prescribes GLP-1 medications for weight loss. It offers semaglutide and tirzepatide as weekly injections plus oral disintegrating tablets (ODT) and liquid drops, and liraglutide as a daily injection. The drops and ODT forms help patients avoid self-injecting or get treatment where injectable shipping is restricted. Care includes in-depth consults and comprehensive blood testing, with mobile phlebotomy. Medical director is Dr. Justin Saya. GLP-1 pricing and state coverage are not published online.
Read our full Defy Medical review →About CoreAge Rx
CoreAge Rx offers LegitScript-verified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.
Read our full CoreAge Rx review →Pros & Cons
Defy Medical
What we like
- Multiple GLP-1 options: semaglutide, tirzepatide, liraglutide
- Offers injection, ODT, and oral drop delivery forms
- Comprehensive blood testing and named medical director
- Established clinic with strong Trustpilot review volume
Watch-outs
- GLP-1 pricing not published on the website
- States served and shipping limits not disclosed
- Compounded versus brand status not stated online
- Lab-heavy, consult-first model may cost more upfront
CoreAge Rx
What we like
- LegitScript certified — rigorous pharmacy standards
- Free 2-day shipping nationwide
- Both semaglutide and tirzepatide available
- Lowest per-month pricing in the compounded segment
- 24/7 support team
- All 50 states covered
Watch-outs
- Compounded only — no brand-name Ozempic or Wegovy
- Newer brand with fewer independent reviews than legacy players
Our Verdict
CoreAge Rx edges out Defy Medical with a higher overall score of 8.3/10 and is particularly strong for best overall value. Defy Medical remains a solid alternative, especially if you're looking for GLP-1 in injection, ODT, or drop forms with thorough lab workups.
Choose Defy Medical if…
You want GLP-1 in injection, ODT, or drop forms with thorough lab workups.
Choose CoreAge Rx if…
You want best overall value and a starting price around $99/mo.
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Mainstream telehealth GLP-1 access
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From $149/mo
Get started →TMates
Nationwide compounded GLP-1 availability including Puerto Rico
From $249/mo
Get started →Defy Medical vs CoreAge Rx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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