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CoreAge Rx vs Synergy Rx

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
CoreAge Rx logo

CoreAge Rx

8.3
★★★★4.2/5

Best for: best overall value

Visit CoreAge Rx
VS
Synergy Rx logo

Synergy Rx

7.7
★★★3.9/5

Best for: broadest drug catalog in the Lion MD white-label cluster

Visit Synergy Rx

CoreAge Rx and Synergy Rx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, CoreAge Rx starts lower at $99/mo versus $199/mo, and CoreAge Rx edges ahead overall (8.3 vs 7.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

CoreAge Rx

Injectable, monthly auto-refill (flat across all dosages)Compounded
$99/mo
semaglutide

Re-verified 2026-08-05: homepage + Preventive Longevity section both show "Semaglutide — Starting at $99/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

Injectable, monthly auto-refill (flat across all dosages)Compounded
$149/mo
tirzepatide

Re-verified 2026-08-05: homepage GLP-1 hero + Preventive Longevity section both show "Tirzepatide — Starting at $149/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

Synergy Rx

Starting atCompounded
$199/mo
semaglutide

$100 welcome credit applied automatically at checkout — no code needed. Free shipping.

Starting atCompounded
$349/mo
tirzepatide

$100 welcome credit applied automatically at checkout — no code needed.

Starting atCompounded · oral
$299/mo
semaglutide

Oral dissolving tablet. $100 welcome credit applied automatically at checkout.

Starting atCompounded · oral
$399/mo
tirzepatide

Oral dissolving tablet. $100 welcome credit applied automatically at checkout.

Starting atCompounded
$499/mo
semaglutide

Brand-name pen. $100 welcome credit applied automatically at checkout.

Starting atCompounded
$947/mo
semaglutide

Brand-name pen. $100 welcome credit applied automatically at checkout.

Starting atCompounded
$947/mo
tirzepatide

Brand-name pen. $100 welcome credit applied automatically at checkout.

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What’s included

CoreAge Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Synergy Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

CoreAge Rx

8.3/10

Overall

Synergy Rx

7.7/10

Value25%

8.5A
vs
B
7.0

Effectiveness25%

8.5A
vs
B
8.5

User Experience15%

8.5A
vs
B
7.5

Trust & Safety15%

7.8A
vs
B
7.8

Accessibility10%

8.0A
vs
B
8.5

Support10%

8.4A
vs
B
6.9

Features & Coverage

FeatureCoreAge RxSynergy Rx
Starting Price$99/mo$199/mo
Features6 features6 features
States Available5050
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About CoreAge Rx

CoreAge Rx offers LegitScript-verified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.

Read our full CoreAge Rx review →

About Synergy Rx

Synergy Rx (CareGLP platform, synergyrx.co) is a Wyoming-registered telehealth platform serving 50,000+ patients with compounded semaglutide ($199), tirzepatide ($349), and brand-name Ozempic ($499), Wegovy ($947), and Mounjaro ($947). Runs on the shared Lion MD clinician + 4-pharmacy network with Breeze Meds and Care Bare Rx.

Read our full Synergy Rx review →

Pros & Cons

CoreAge Rx

What we like

  • LegitScript certified — rigorous pharmacy standards
  • Free 2-day shipping nationwide
  • Both semaglutide and tirzepatide available
  • Lowest per-month pricing in the compounded segment
  • 24/7 support team
  • All 50 states covered

Watch-outs

  • Compounded only — no brand-name Ozempic or Wegovy
  • Newer brand with fewer independent reviews than legacy players

Synergy Rx

What we like

  • Broad catalog: compounded sema/tirz in injection and oral dissolving tablet, plus brand Ozempic, Wegovy, and Mounjaro
  • Claims 50,000+ patients as of late 2025
  • Available in all 50 states, subject to state telehealth rules
  • Same medical team as Breeze Meds and Care Bare Rx (Dr. Carr and Dr. Tenbrink via Lion MD)
  • Four named 503A pharmacy partners (Belmar, Strive, Epiq Scripts, Casa Pharma Rx)
  • LegitScript Certified

Watch-outs

  • Same clinician network and pharmacies as Breeze Meds and Care Bare Rx — three brands on one underlying operation
  • Mandatory individual arbitration + class-action waiver (30-day opt-out from signup)
  • Consultation fees non-refundable and all prescription sales final
  • Disclaims liability for third-party pharmacy medication quality
  • Full active-state list requires contacting support, not published
  • Correct site is synergyrx.co — synergyrx.com is an unrelated parked domain

Our Verdict

Winner: CoreAge Rx

CoreAge Rx edges out Synergy Rx with a higher overall score of 8.3/10 and is particularly strong for best overall value. Synergy Rx remains a solid alternative, especially if you're looking for broadest drug catalog in the Lion MD white-label cluster.

Choose CoreAge Rx if…

You want best overall value and a starting price around $99/mo.

Choose Synergy Rx if…

You want broadest drug catalog in the Lion MD white-label cluster and a starting price around $199/mo.

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7.7

Synergy Rx

Broadest drug catalog in the Lion MD white-label cluster

8.1

RxSpan MD

Physician-led, pharmacy-transparent compounded GLP-1 with brand-name options

8.0

Strut Health

Oral-lozenge compounded GLP-1 access

CoreAge Rx vs Synergy Rx: FAQ

CoreAge Rx is cheaper. Its lowest ongoing monthly cash price is $99/mo, compared with $199/mo for Synergy Rx. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
CoreAge Rx scores higher overall at 8.3/10 versus 7.7/10, and is particularly strong for best overall value. That said, Synergy Rx is a better fit if you want broadest drug catalog in the Lion MD white-label cluster.
CoreAge Rx and Synergy Rx both list availability in 50 states.
Both CoreAge Rx and Synergy Rx are affiliate partners, meaning we may earn a commission if you sign up through our links. Our scores are assigned editorially using the same six-dimension framework for every provider — partnership never changes a score. We disclose every commercial relationship.
For Semaglutide, CoreAge Rx is cheaper at $99/mo versus $199/mo at Synergy Rx.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring CoreAge Rx and Synergy Rx head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.