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CoreAge Rx vs SkyRx

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
CoreAge Rx logo

CoreAge Rx

8.3
★★★★4.2/5

Best for: best overall value

Visit CoreAge Rx
VS

SkyRx

6.7
★★★☆☆3.4/5

Best for: all-inclusive compounded semaglutide with supplies included

Visit SkyRx

CoreAge Rx and SkyRx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, CoreAge Rx starts lower at $99/mo versus $199/mo, and CoreAge Rx edges ahead overall (8.3 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

CoreAge Rx

Injectable, monthly auto-refill (flat across all dosages)Compounded
$99/mo
semaglutide

Re-verified 2026-08-05: homepage + Preventive Longevity section both show "Semaglutide — Starting at $99/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

Injectable, monthly auto-refill (flat across all dosages)Compounded
$149/mo
tirzepatide

Re-verified 2026-08-05: homepage GLP-1 hero + Preventive Longevity section both show "Tirzepatide — Starting at $149/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

SkyRx

All doses (flat)Compounded
$199/mo
semaglutide

199/mo on a 12-month prepaid subscription; includes med, supplies, visit, shipping

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What’s included

CoreAge Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

SkyRx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

CoreAge Rx

8.3/10

Overall

SkyRx

6.7/10

Value25%

8.5A
vs
B
7.0

Effectiveness25%

8.5A
vs
B
6.5

User Experience15%

8.5A
vs
B
7.0

Trust & Safety15%

7.8A
vs
B
6.5

Accessibility10%

8.0A
vs
B
6.0

Support10%

8.4A
vs
B
7.0

Features & Coverage

FeatureCoreAge RxSkyRx
Starting Price$99/mo$199/mo
Features6 features6 features
States Available50Not disclosed
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About CoreAge Rx

CoreAge Rx offers LegitScript-verified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.

Read our full CoreAge Rx review →

About SkyRx

SkyRx (sky-rx.co) is a US telehealth weight-loss program offering compounded semaglutide as an injection or oral drops, with compounded tirzepatide listed as coming soon. Pricing starts at 199 dollars per month on a 12-month subscription paid upfront, and the single monthly price bundles medication, supplies, doctor visit and shipping with no insurance needed. Medication is dispensed by FDA-registered 503B compounding pharmacies. GLP-1s are not yet available in all 50 states. Support is by phone at 855-759-7979 and email; the company is based in Draper, Utah.

Read our full SkyRx review →

Pros & Cons

CoreAge Rx

What we like

  • LegitScript certified — rigorous pharmacy standards
  • Free 2-day shipping nationwide
  • Both semaglutide and tirzepatide available
  • Lowest per-month pricing in the compounded segment
  • 24/7 support team
  • All 50 states covered

Watch-outs

  • Compounded only — no brand-name Ozempic or Wegovy
  • Newer brand with fewer independent reviews than legacy players

SkyRx

What we like

  • All-inclusive 199 dollars per month covers medication, supplies, doctor visit and shipping
  • Offers both injectable and oral semaglutide, dispensed by FDA-registered 503B pharmacies
  • Same-day shipping for orders before 2pm ET in temperature-controlled packaging

Watch-outs

  • 199 dollars pricing requires a 12-month subscription paid upfront
  • Tirzepatide only listed as coming soon
  • GLP-1s not yet available in all 50 states; specific states not listed

Our Verdict

Winner: CoreAge Rx

CoreAge Rx edges out SkyRx with a higher overall score of 8.3/10 and is particularly strong for best overall value. SkyRx remains a solid alternative, especially if you're looking for all-inclusive compounded semaglutide with supplies included.

Choose CoreAge Rx if…

You want best overall value and a starting price around $99/mo.

Choose SkyRx if…

You want all-inclusive compounded semaglutide with supplies included and a starting price around $199/mo.

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CoreAge Rx vs SkyRx: FAQ

CoreAge Rx is cheaper. Its lowest ongoing monthly cash price is $99/mo, compared with $199/mo for SkyRx. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
CoreAge Rx scores higher overall at 8.3/10 versus 6.7/10, and is particularly strong for best overall value. That said, SkyRx is a better fit if you want all-inclusive compounded semaglutide with supplies included.
CoreAge Rx lists availability in 50 states, while SkyRx's state list is not publicly listed.
CoreAge Rx is an affiliate partner (we may earn a commission on sign-ups through our links); SkyRx is not. Either way, we rank providers editorially with the same scoring framework and disclose every partnership — being a partner does not buy a higher score.
For Semaglutide, CoreAge Rx is cheaper at $99/mo versus $199/mo at SkyRx.

Key terms, explained

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Continue exploring CoreAge Rx and SkyRx head-to-heads in the same category.

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