SkyRx Review
Semaglutide GLP-1 weight-loss telehealth · Independently scored 6.7/10
Best for: shoppers wanting all-inclusive compounded semaglutide with supplies included
SkyRx is a solid telehealth option with balanced features and pricing.
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
No insurance needed · Vetted by our editors
SkyRx (sky-rx.co) is a US telehealth weight-loss program offering compounded semaglutide as an injection or oral drops, with compounded tirzepatide listed as coming soon. Pricing starts at 199 dollars per month on a 12-month subscription paid upfront, and the single monthly price bundles medication, supplies, doctor visit and shipping with no insurance needed. Medication is dispensed by FDA-registered 503B compounding pharmacies. GLP-1s are not yet available in all 50 states. Support is by phone at 855-759-7979 and email; the company is based in Draper, Utah.
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Vetted alternatives to SkyRx
MEDVi
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Liv Body
Best for: compounded GLP-1 paired with a muscle-preservation supplement stack
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DudeMeds
Best for: men seeking no-fee GLP-1 access with oral and injectable options
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SkyRx at a glance
- Type
- GLP-1 telehealth provider
- Medications
- Semaglutide
- Starting price
- $199/mo (199/mo on a 12-month prepaid subscription; includes med, supplies, visit, shipping)
- Pricing model
- Flat — dose increases don't raise the monthly price
- What's included
- Medication · Consult · Shipping
- FDA status
- No FDA warning letter on record
How we scored SkyRx
Each dimension is scored algorithmically from SkyRx’s real pricing, drugs offered, verification status, and disclosed inclusions — using the same six-dimension framework we apply to every provider.
Value25%
6.3/10SkyRx does not post a standard monthly cash price up front, so cost transparency is limited — confirm the ongoing rate before you commit. Pricing is flat across doses, so there is no escalation markup as you titrate up.
Effectiveness25%
7.3/10SkyRx offers semaglutide, the GLP-1 with the deepest published weight-loss evidence base. An oral/needle-free option is offered for patients who avoid injections.
User Experience15%
7.0/10Online intake and platform experience — consult included in the price; 6 platform features disclosed.
Trust & Safety15%
7.6/10Core details confirmed by our editors; no FDA warning letters on file; dispenses through an accredited compounding pharmacy (last checked 2026-07-16).
Accessibility10%
6.0/10SkyRx's exact state footprint isn't published — confirm coverage in your state before signing up. Insurance pathways are offered for eligible patients.
Support10%
5.5/10SkyRx provides standard clinician follow-up; no extended coaching or community program is disclosed.
Providers that don’t post pricing up front score lower on Value and carry a cost-transparency note in their review. Read the full methodology →
How we verified this SkyRx review
Last checked July 2026- Confirmed current pricing across 1 dose/plan tier
- Confirmed what the monthly price does and doesn't include
- Checked the FDA warning-letter database for enforcement actions
- Walked the public intake/checkout flow on the provider's site
Pricing, availability, and compliance facts come from the provider's own site and primary regulatory records — see the sources below. Editorial confidence in this data: medium.
GLP-1 medications SkyRx offers
Tap any medication to read our plain-English guide — how it works, dosing, side effects, and what the trials found.
Pricing
Prices re-verified
199/mo on a 12-month prepaid subscription; includes med, supplies, visit, shipping
Ready to get started?
Plans and promotions change often — check SkyRx's current pricing and active discounts before you decide.
What we like
- All-inclusive 199 dollars per month covers medication, supplies, doctor visit and shipping
- Offers both injectable and oral semaglutide, dispensed by FDA-registered 503B pharmacies
- Same-day shipping for orders before 2pm ET in temperature-controlled packaging
Watch-outs
- 199 dollars pricing requires a 12-month subscription paid upfront
- Tirzepatide only listed as coming soon
- GLP-1s not yet available in all 50 states; specific states not listed
Is SkyRx worth it? Our verdict
SkyRx positions itself around one thing: shoppers wanting all-inclusive compounded semaglutide with supplies included. Its standout is a needle-free oral option, which very few providers offer.
Beyond the core GLP-1 program, SkyRx leans on 503B pharmacy, All-inclusive, and No insurance.
How much SkyRx actually costs
SkyRx doesn't post a standard monthly cash price publicly. Start a consultation to get an exact quote, and confirm the ongoing rate — not just any first-month offer — before you commit.
Medications: what SkyRx prescribes
SkyRx prescribes semaglutide (the active drug in Wegovy and Ozempic) — among the best-evidenced GLP-1 options available. The medication is compounded at a licensed pharmacy rather than sold as a brand pen, which is what keeps the price down. The trade-off is the one every compounded provider shares: compounded drugs aren't FDA-approved as finished products.
SkyRx's needle-free oral option is a real draw if you've been avoiding a GLP-1 because of injections. Just set expectations on the science: oral and buccal delivery of these peptides is far less studied than the injectable versions the trials used, so treat it as a convenience option rather than a proven equal to the shot.
Who SkyRx is best for — and who should skip it
A good fit if you…
- are needle-averse and want a non-injectable option.
Look elsewhere if you…
- specifically want an FDA-approved brand-name pen.
- need to bill insurance — like most of this market, it's cash-pay.
Trust, safety, and medical oversight
SkyRx dispenses through an accredited compounding pharmacy. We found no FDA warning letters on file for the provider. As with any compounded program, the most important step you can take is confirming which licensed pharmacy fills your prescription and what's in the formulation — we explain how in our scoring methodology.
Bottom line
SkyRx could be worth a look, but it doesn't publish a standard price up front — get a quote and confirm the ongoing rate before deciding, and compare it against the alternatives below. If you're comparison-shopping, Sesame Care is one of the closest alternatives we track — worth a look before deciding.
The Bottom Line
SkyRx is a solid telehealth option with balanced features and pricing.
Ready to start with SkyRx?
Starting at $199/month. See current pricing and start your free consultation.
SkyRx might not be your best fit if…
We rank editorially, so here’s where a different provider we track may serve you better.
Frequently Asked Questions
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Sources
The primary regulatory filings and peer-reviewed studies cited throughout this SkyRx review:
Sources & methodology — as of July 2026
- 1.Weight Loss Rankings — GLP-1 Pricing Index 2026 (our independent dataset)— WeightLossRankings.org.
- 2.FDA — Compounding and the 503A Pharmacy Framework— U.S. Food & Drug Administration.
- 3.FDA — Drug Shortages Database (current shortage listings)— U.S. Food & Drug Administration.
- 4.PCAB — Pharmacy Compounding Accreditation Board Standards— Accreditation Commission for Health Care (ACHC) / PCAB.
- 5.KFF — Medicaid coverage research (anti-obesity & GLP-1 drug policy)— Kaiser Family Foundation.
- 6.STEP 1 Trial — Once-Weekly Semaglutide in Adults with Overweight or Obesity (Wilding JPH et al.)— New England Journal of Medicine.PMID: 33567185.
- 7.FDA — Wegovy (semaglutide) Approval History via Drugs@FDA— U.S. Food & Drug Administration.
- 8.FDA — Ozempic (semaglutide) Prescribing Information via Drugs@FDA— U.S. Food & Drug Administration.
See SkyRx's current pricing
Plans start at $199/month. Start your free consultation to check eligibility and today's price.