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CoreAge Rx vs Defy Medical

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
CoreAge Rx logo

CoreAge Rx

8.3
★★★★4.2/5

Best for: best overall value

Visit CoreAge Rx
VS
Defy Medical logo

Defy Medical

7.0
★★★3.5/5

Best for: Patients wanting GLP-1 in injection, ODT, or drop forms with thorough lab workups

Visit Defy Medical

CoreAge Rx and Defy Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, CoreAge Rx starts at $149/mo, and CoreAge Rx edges ahead overall (8.3 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

CoreAge Rx

0.25mgCompounded
$149/mo
semaglutide
0.5mgCompounded
$199/mo
semaglutide
1mgCompounded
$249/mo
semaglutide
1.7mgCompounded
$299/mo
semaglutide
2.5mgCompounded
$349/mo
tirzepatide

Defy Medical

Pricing not publicly listed.

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What’s included

CoreAge Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Defy Medical

Inclusions not disclosed.

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

CoreAge Rx

8.3/10

Overall

Defy Medical

7.0/10

Value25%

8.5A
vs
B
6.5

Effectiveness25%

8.5A
vs
B
7.5

User Experience15%

8.5A
vs
B
6.5

Trust & Safety15%

7.8A
vs
B
7.0

Accessibility10%

8.0A
vs
B
7.0

Support10%

8.4A
vs
B
7.4

Features & Coverage

FeatureCoreAge RxDefy Medical
Starting Price$149/mo
Features6 features8 features
States Available50Not disclosed
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About CoreAge Rx

CoreAge Rx offers LegitScript-verified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.

Read our full CoreAge Rx review →

About Defy Medical

Defy Medical is a long-running telehealth clinic, best known for hormone replacement, that also prescribes GLP-1 medications for weight loss. It offers semaglutide and tirzepatide as weekly injections plus oral disintegrating tablets (ODT) and liquid drops, and liraglutide as a daily injection. The drops and ODT forms help patients avoid self-injecting or get treatment where injectable shipping is restricted. Care includes in-depth consults and comprehensive blood testing, with mobile phlebotomy. Medical director is Dr. Justin Saya. GLP-1 pricing and state coverage are not published online.

Read our full Defy Medical review →

Pros & Cons

CoreAge Rx

What we like

  • LegitScript certified — rigorous pharmacy standards
  • Free 2-day shipping nationwide
  • Both semaglutide and tirzepatide available
  • Lowest per-month pricing in the compounded segment
  • 24/7 support team
  • All 50 states covered

Watch-outs

  • Compounded only — no brand-name Ozempic or Wegovy
  • Newer brand with fewer independent reviews than legacy players

Defy Medical

What we like

  • Multiple GLP-1 options: semaglutide, tirzepatide, liraglutide
  • Offers injection, ODT, and oral drop delivery forms
  • Comprehensive blood testing and named medical director
  • Established clinic with strong Trustpilot review volume

Watch-outs

  • GLP-1 pricing not published on the website
  • States served and shipping limits not disclosed
  • Compounded versus brand status not stated online
  • Lab-heavy, consult-first model may cost more upfront

Our Verdict

Winner: CoreAge Rx

CoreAge Rx edges out Defy Medical with a higher overall score of 8.3/10 and is particularly strong for best overall value. Defy Medical remains a solid alternative, especially if you're looking for Patients wanting GLP-1 in injection, ODT, or drop forms with thorough lab workups.

Choose CoreAge Rx if…

You want best overall value and a starting price around $149/mo.

Choose Defy Medical if…

You want Patients wanting GLP-1 in injection, ODT, or drop forms with thorough lab workups.

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CoreAge Rx vs Defy Medical: FAQ

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