CLYR Health vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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CLYR Health
Best for: Flat-rate compounded GLP-1 with pricing that does not increase as your dose goes up
Visit CLYR Health →
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →CLYR Health and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $229/mo, and NewSelf edges ahead overall (8.3 vs 7.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
CLYR Health
Flat any-dose $229/mo; 3-month prepay $189/mo ($567 billed once)
$249/mo standard dose (up to 3mL); 3-month prepay $199/mo; higher dose 4-8mL $349/mo
NewSelf
All dosages same price
All dosages same price
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What’s included
CLYR Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Not disclosed
Lab work
Not disclosed
Coaching
Not disclosed
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
CLYR Health
7.7/10
NewSelf
8.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | CLYR Health | NewSelf |
|---|---|---|
| Starting Price | $229/mo | ✓$100/mo |
| Features | 6 features | 6 features |
| States Available | Not disclosed | 49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About CLYR Health
CLYR Health is a Florida-based telehealth pharmacy offering compounded GLP-1 weight-loss injections alongside sexual-health, longevity and wellness treatments. It sells compounded semaglutide + B12 from $229/mo and compounded tirzepatide + B12 from $249/mo on flat 'any dose, one price' billing, with 3-month prepay plans that lower the effective rate. Brand Zepbound and oral GLP-1 options are also listed. LegitScript Certified and fulfilled by a named 503A pharmacy.
Read our full CLYR Health review →About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →Pros & Cons
CLYR Health
What we like
- Flat 'any dose, one price' billing so the monthly cost does not rise as your dose climbs
- LegitScript Certified with a named 503A pharmacy partner (The Pharmacy Hub, Miami FL) and MD Integrations clinicians
- 3-month prepay drops semaglutide to $189/mo and tirzepatide to $199/mo
Watch-outs
- State availability gated behind intake; not published on the marketing site
- Standing monthly rates ($229-249) run above the cheapest compounded competitors
- Broad catalog (weight loss, sexual health, longevity) rather than a weight-loss specialist
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out CLYR Health with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. CLYR Health remains a solid alternative, especially if you're looking for Flat-rate compounded GLP-1 with pricing that does not increase as your dose goes up.
Choose CLYR Health if…
You want Flat-rate compounded GLP-1 with pricing that does not increase as your dose goes up and a starting price around $229/mo.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
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DudeMeds
Men seeking no-fee GLP-1 access with oral and injectable options
From $175/mo
Get started →Oak
Compounded semaglutide and tirzepatide at a flat monthly price
From $119/mo
Get started →Bodybuilding Health+
Fitness-brand compounded GLP-1 with hormone and performance programs
From $179/mo
Get started →CLYR Health vs NewSelf: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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