Center for Medical Weight Loss (CMWL) vs Amazon One Medical
An in-depth comparison of two leading GLP-1 Providers
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Center for Medical Weight Loss (CMWL)
Best for: flat any-dose compounded glp-1 from an established program
Visit Center for Medical Weight Loss (CMWL) →
Amazon One Medical
Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery
Visit Amazon One Medical →Center for Medical Weight Loss (CMWL) and Amazon One Medical are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, both start around $149/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.4 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Center for Medical Weight Loss (CMWL)
Standing month\u002dto\u002dmonth rate. /compounded\u002dsemaglutide publishes '3 month plan $116/month | Monthly plan $149/month'; the 3\u002dmonth plan bills for 3 months at $116/mo (349 dollars total). Billing on 3\u002dmonth plans runs every 10 weeks for a 12\u002dweek supply, per the site's own note.
Standing month\u002dto\u002dmonth rate. /compounded\u002dtirzepatide publishes '3 month plan $159/month | Monthly plan $239/month'; the 3\u002dmonth plan bills for 3 months at $159/mo (477 dollars total). Same 10\u002dweek billing cycle on 3\u002dmonth plans.
Amazon One Medical
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What’s included
Center for Medical Weight Loss (CMWL)
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Center for Medical Weight Loss (CMWL)
7.4/10
Amazon One Medical
8.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Center for Medical Weight Loss (CMWL) | Amazon One Medical |
|---|---|---|
| Starting Price | $149/mo | $149/mo |
| Features | 6 features | 6 features |
| States Available | Not disclosed | 50 |
| Compounded | ✓ Yes | — |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Center for Medical Weight Loss (CMWL)
Center for Medical Weight Loss (CMWL) runs a 100 percent online, physician-supervised GLP-1 program using compounded semaglutide and tirzepatide with flat any-dose pricing. Month-to-month is 149 dollars for semaglutide and 239 dollars for tirzepatide, dropping to 116 and 159 dollars per month on a three-month plan, with lower-cost microdosing also offered. Prescriptions are typically approved within 24 hours with free shipping. Some states are ineligible. Compounded meds are not FDA-approved.
Read our full Center for Medical Weight Loss (CMWL) review →About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →Pros & Cons
Center for Medical Weight Loss (CMWL)
What we like
- Very competitive flat any-dose pricing (semaglutide from 116 dollars per month, tirzepatide from 159 dollars per month)
- Established Center for Medical Weight Loss brand with physician supervision and clinical support
- Fast 24-hour approvals and free three to five day shipping
Watch-outs
- Some states are ineligible and the eligible-state list is not published
- Compounding pharmacy is not named publicly
- Lowest per-month prices require a three-month prepaid commitment
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Our Verdict
Amazon One Medical edges out Center for Medical Weight Loss (CMWL) with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. Center for Medical Weight Loss (CMWL) remains a solid alternative, especially if you're looking for flat any-dose compounded glp-1 from an established program.
Choose Center for Medical Weight Loss (CMWL) if…
You want flat any-dose compounded glp-1 from an established program and a starting price around $149/mo.
Choose Amazon One Medical if…
You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.
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Gala
Compounded GLP-1/GIP combo on a yearly plan with free shipping
From $149/mo
Get started →Found
Mainstream telehealth GLP-1 access
From $99/mo
Get started →Breeze Meds
Compounded GLP-1 access with named prescribers and 4-pharmacy network
From $199/mo
Get started →Center for Medical Weight Loss (CMWL) vs Amazon One Medical: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.