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Apex MD vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Apex MD

7.2
★★★3.6/5

Best for: people who want nationwide access to compounded glp-1 with unlimited visits and labs included

Visit Apex MD
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

Apex MD and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $299/mo, and NewSelf edges ahead overall (8.3 vs 7.2 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Apex MD

All doses (injection)Compounded
$299/mo
semaglutide

weekly injection, includes NAD/B-12/L-Carnitine, month-to-month

All doses (injection)Compounded
$399/mo
tirzepatide

weekly injection, month-to-month

All doses (oral)Compounded
$349/mo
semaglutide

daily oral

All doses (oral)Compounded
$419/mo
tirzepatide

daily oral

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

Apex MD

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Apex MD

7.2/10

Overall

NewSelf

8.3/10

Value25%

6.8A
vs
B
9.0

Effectiveness25%

7.5A
vs
B
8.0

User Experience15%

7.2A
vs
B
8.0

Trust & Safety15%

6.5A
vs
B
8.3

Accessibility10%

8.5A
vs
B
8.5

Support10%

7.5A
vs
B
7.9

Features & Coverage

FeatureApex MDNewSelf
Starting Price$299/mo$100/mo
Features8 features6 features
States Available5149
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About Apex MD

Apex MD is a US virtual telemedicine platform licensed in all 50 states that prescribes compounded GLP-1 medications for weight loss. Weekly injections are 299 dollars per month for compounded semaglutide and 399 dollars per month for compounded tirzepatide; daily oral versions are 349 dollars per month for semaglutide and 419 dollars per month for tirzepatide. Compounds are formulated with added NAD, B-12 and L-Carnitine. Plans include unlimited provider visits and Labcorp labs at no extra fee, with medication delivery typically in under four business days. GLP-1 microdosing is also offered.

Read our full Apex MD review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

Apex MD

What we like

  • Licensed in all 50 states
  • Unlimited provider visits and Labcorp labs included in the plan
  • Both semaglutide and tirzepatide, injectable or oral
  • Medication delivery typically in under four business days

Watch-outs

  • Compounds bundle NAD, B-12 and L-Carnitine rather than a single-ingredient GLP-1
  • Does not publicly name its compounding pharmacy or list an accreditation seal

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out Apex MD with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. Apex MD remains a solid alternative, especially if you're looking for people who want nationwide access to compounded glp-1 with unlimited visits and labs included.

Choose Apex MD if…

You want people who want nationwide access to compounded glp-1 with unlimited visits and labs included and a starting price around $299/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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Apex MD vs NewSelf: FAQ

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