Amazon One Medical vs Velvet Rx
In our scoring, Amazon One Medical edges ahead overall (8.5 vs 6.6 out of 10).
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Key differences
- Price
- Amazon One Medical $199/mo for brand-name Wegovy / Ozempic; Velvet Rx $299/mo for compounded semaglutide (different medications, so not compared on price)
- Coverage
- Amazon One Medical 50 states (Velvet Rx doesn't publish a state list)
- Included
- Amazon One Medical: clinician visits, shipping (not included: medication, labs); Velvet Rx: medication, clinician visits, shipping
Amazon One Medical
Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery
Brand-name Wegovy / Ozempic
$199
billed every 4 weeks
Our score 8.5/10
Velvet Rx
Best for price-first shoppers who want a cheap first month of GLP-1 injections or tablets
semaglutide
$299
billed every 4 weeks · $99 first month
Our score 6.6/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Amazon One Medical
Velvet Rx
Price
Semaglutide / month
Not listed
$299/mo
billed every 4 weeks · $99 first month
Tirzepatide / month
Not listed
$359/mo
billed every 4 weeks · $179 first month
Oral semaglutide / month
Not listed
$349/mo
$149 first month
Brand Wegovy / Ozempic / month
$199/mo
billed every 4 weeks
Not listed
Brand Zepbound / Mounjaro / month
$299/mo
billed every 4 weeks
Not listed
Brand Wegovy pill / Rybelsus / month
$149/mo
Not listed
Brand Foundayo / month
$149/mo
Not listed
Coverage
State availability
50 states
List not published
Oral option listed
Yes
Yes
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Not listed
Included in the price
Clinician visits, shipping
Not included: medication, labs
Medication, clinician visits, shipping
FSA/HSA accepted
Not listed
Yes
Terms & safety
Price shown
Before intake
Before intake
Lab work
Required
Not disclosed
Cancel anytime
Not disclosed
Yes
Minimum commitment
Not disclosed
Monthly auto-renewing subscription
Refunds
Not disclosed
'processed orders (including for medications ...) may not be eligible for refunds; discounted products or services may be non-refundable'
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
October 2026
Every dose and plan: Amazon One Medical · Velvet Rx
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Amazon One Medical if…
- Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which Velvet Rx doesn't price
- Publishes its full state list (50 states)
- Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible
What to weigh up
- Price doesn't include medication
- Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
Choose Velvet Rx if…
- Lists compounded semaglutide, compounded tirzepatide and oral compounded semaglutide, which Amazon One Medical doesn't price
- Price includes medication; Amazon One Medical's doesn't
- Accepts FSA/HSA cards
What to weigh up
- No published state list; confirm yours at signup
- Regular prices ($299 to $359 a month) are well above the first-month rate and on the high side for compounded GLP-1
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
Velvet Rx
6.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
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From $219/mo
Get started →Found
Compounded GLP-1 with medication included from $169/mo cash, plus insurance help for brand GLP-1s
Read full review →From $169/mo
Get started →GobyMeds
No-membership, no-auto-renew compounded GLP-1 orders, from about $99/mo on a 3-month bundle
Read full review →From $169/mo
Get started →Amazon One Medical vs Velvet Rx: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.