Amazon One Medical vs Superpower
In our scoring, Amazon One Medical edges ahead overall (8.5 vs 7.1 out of 10).
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Key differences
- Price
- Amazon One Medical $199/mo for brand-name Wegovy / Ozempic; Superpower $229/mo for compounded semaglutide (different medications, so not compared on price)
- Coverage
- Amazon One Medical 50 states; Superpower 41 states + DC (only Amazon One Medical: Alaska, Arkansas, Hawaii and 6 more · only Superpower: District of Columbia)
- Included
- Amazon One Medical: clinician visits, shipping (not included: medication, labs); Superpower: medication, shipping, labs
Amazon One Medical
Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery
Brand-name Wegovy / Ozempic
$199
billed every 4 weeks
Our score 8.5/10

Superpower
Best for Members who want lab testing bundled with a GLP-1 prescription, not just medication
semaglutide
$229
+ separate membership
Our score 7.1/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Amazon One Medical
Superpower
Price
Semaglutide / month
Not listed
$229/mo
+ separate membership
Brand Wegovy / Ozempic / month
$199/mo
billed every 4 weeks
Not listed
Brand Zepbound / Mounjaro / month
$299/mo
billed every 4 weeks
Not listed
Brand Wegovy pill / Rybelsus / month
$149/mo
Not listed
Brand Foundayo / month
$149/mo
Not listed
Separate membership required
Not stated
Yes, not in the listed price
Coverage
State availability
50 states
41 states + DC
Oral option listed
Yes
Not listed
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Not listed
Included in the price
Clinician visits, shipping
Not included: medication, labs
Medication, shipping, labs
FSA/HSA accepted
Not listed
Yes
Terms & safety
Price shown
Before intake
Before intake
Lab work
Required
Not disclosed
Cancel anytime
Not disclosed
Yes
Minimum commitment
Not disclosed
Annual $199 membership that auto-renews; Marketplace medication billed separately
Refunds
Not disclosed
Membership Agreement: 100% refund of the base membership fee if requested by the earlier of 7 days after your first lab results or 45 days after your start date. The general FAQ separately says 'Superpower does not offer refunds at this time.'
Early-cancellation fee
Not disclosed
None
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
October 2026
Show where they differ by stateHide state lists
Only Superpower (DC)
- District of Columbia
Only Amazon One Medical (9 states)
- Alaska
- Arkansas
- Hawaii
- Louisiana
- Mississippi
- North Dakota
- Rhode Island
- South Dakota
- Wyoming
Every dose and plan: Amazon One Medical · Superpower
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 520+ providers' prices on their own sites and email you when tracked prices move.
Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Amazon One Medical if…
- Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which Superpower doesn't price
- Serves 9 states that Superpower doesn't
- Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible
What to weigh up
- Not available in District of Columbia
- Price doesn't include medication and labs

Choose Superpower if…
- Lists compounded semaglutide, which Amazon One Medical doesn't price
- Serves District of Columbia, where Amazon One Medical doesn't
- Price includes medication and labs; Amazon One Medical's doesn't
What to weigh up
- Listed compounded semaglutide price excludes a required membership
- Not available in 9 states that Amazon One Medical serves
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
Superpower
7.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
From $139/mo (4-month plan rate)
Get started →Ro
FDA-approved brand GLP-1s, including the Wegovy pill and Foundayo, with insurance help
Read full review →From $149/mo (+ required membership)
Get started →Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo (+ required membership)
Get started →Amazon One Medical vs Superpower: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring Amazon One Medical and Superpower head-to-heads in the same category.
- Amazon One Medical vs Vytora Health
- Amazon One Medical vs CoreAge Rx
- Amazon One Medical vs Collective
- Superpower vs Vytora Health
Or see the full category ranking, or alternatives to Amazon One Medical and Superpower.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.