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Amazon One Medical vs Superpower

In our scoring, Amazon One Medical edges ahead overall (8.5 vs 7.1 out of 10).

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed

Key differences

Price
Amazon One Medical $199/mo for brand-name Wegovy / Ozempic; Superpower $229/mo for compounded semaglutide (different medications, so not compared on price)
Coverage
Amazon One Medical 50 states; Superpower 41 states + DC (only Amazon One Medical: Alaska, Arkansas, Hawaii and 6 more · only Superpower: District of Columbia)
Included
Amazon One Medical: clinician visits, shipping (not included: medication, labs); Superpower: medication, shipping, labs

How we compare providers

Amazon One Medical logo

Amazon One Medical

Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery

Brand-name Wegovy / Ozempic

$199/mo

billed every 4 weeks

Our score 8.5/10

Superpower logo

Superpower

Best for Members who want lab testing bundled with a GLP-1 prescription, not just medication

semaglutide

$229/mo

+ separate membership

Our score 7.1/10

We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.

Costs & coverage

Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.

Amazon One Medical

Superpower

Price

Semaglutide / month

Not listed

$229/mo

+ separate membership

Brand Wegovy / Ozempic / month

$199/mo

billed every 4 weeks

Not listed

Brand Zepbound / Mounjaro / month

$299/mo

billed every 4 weeks

Not listed

Brand Wegovy pill / Rybelsus / month

$149/mo

Not listed

Brand Foundayo / month

$149/mo

Not listed

Separate membership required

Not stated

Yes, not in the listed price

Coverage

State availability

50 states

41 states + DC

Oral option listed

Yes

Not listed

Brand-name access listed

Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo

Not listed

Included in the price

Clinician visits, shipping

Not included: medication, labs

Medication, shipping, labs

FSA/HSA accepted

Not listed

Yes

Terms & safety

Price shown

Before intake

Before intake

Lab work

Required

Not disclosed

Cancel anytime

Not disclosed

Yes

Minimum commitment

Not disclosed

Annual $199 membership that auto-renews; Marketplace medication billed separately

Refunds

Not disclosed

Membership Agreement: 100% refund of the base membership fee if requested by the earlier of 7 days after your first lab results or 45 days after your start date. The general FAQ separately says 'Superpower does not offer refunds at this time.'

Early-cancellation fee

Not disclosed

None

FDA warning letters

None on record

None on record

Provider facts checked

October 2026

October 2026

Show where they differ by state

Only Superpower (DC)

  • District of Columbia

Only Amazon One Medical (9 states)

  • Alaska
  • Arkansas
  • Hawaii
  • Louisiana
  • Mississippi
  • North Dakota
  • Rhode Island
  • South Dakota
  • Wyoming

Every dose and plan: Amazon One Medical · Superpower

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Which fits your priorities?

Only the points where these two differ, from the table above and each provider’s record.

Amazon One Medical logo

Choose Amazon One Medical if…

  • Lists brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro and brand-name Wegovy pill / Rybelsus, which Superpower doesn't price
  • Serves 9 states that Superpower doesn't
  • Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible

What to weigh up

  • Not available in District of Columbia
  • Price doesn't include medication and labs
Superpower logo

Choose Superpower if…

  • Lists compounded semaglutide, which Amazon One Medical doesn't price
  • Serves District of Columbia, where Amazon One Medical doesn't
  • Price includes medication and labs; Amazon One Medical's doesn't

What to weigh up

  • Listed compounded semaglutide price excludes a required membership
  • Not available in 9 states that Amazon One Medical serves

Explore the scoring factors

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Amazon One Medical

8.5/10

Overall

Superpower

7.1/10

Value25%

8.5A
vs
B
7.0

Effectiveness25%

8.5A
vs
B
7.0

User Experience15%

8.0A
vs
B
7.0

Trust & Safety15%

8.8A
vs
B
7.0

Accessibility10%

9.5A
vs
B
7.5

Support10%

8.0A
vs
B
7.5

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Amazon One Medical vs Superpower: FAQ

Amazon One Medical scores higher overall at 8.5/10 versus 7.1/10, and is particularly strong for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery. That said, Superpower is a better fit if you want Members who want lab testing bundled with a GLP-1 prescription, not just medication.
Neither Amazon One Medical nor Superpower is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
Not at a published price. Amazon One Medical lists brand-name Foundayo, brand-name Wegovy pill / Rybelsus, brand-name Wegovy / Ozempic, brand-name Zepbound / Mounjaro; Superpower lists compounded semaglutide.
Both serve 41 states. Only Amazon One Medical serves Alaska, Arkansas, Hawaii, Louisiana, Mississippi, North Dakota and 3 more. Only Superpower serves District of Columbia.
Amazon One Medical doesn't state its cancellation terms. Superpower: cancel anytime (yes), minimum commitment (Annual $199 membership that auto-renews; Marketplace medication billed separately), early-cancellation fee (none). Check the provider's own terms before you buy.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring Amazon One Medical and Superpower head-to-heads in the same category.

Or see the full category ranking, or alternatives to Amazon One Medical and Superpower.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.