Amazon One Medical vs Ounce
An in-depth comparison of two leading GLP-1 Providers
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Amazon One Medical
Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery
Visit Amazon One Medical →
Ounce
Best for: people who want to lock in a posted all-in GLP-1 price with labs included before the service opens
Visit Ounce →Amazon One Medical and Ounce are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $249/mo, and Amazon One Medical edges ahead overall (8.5 vs 6.6 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Amazon One Medical
Ounce
Launch price. 12, 24 and 52-week plans cost $657, $1,194 and $2,327 ($219, $199 and $179 per 4-week shipment)
Launch price. 12, 24 and 52-week plans cost $777, $1,434 and $2,717 ($259, $239 and $209 per 4-week shipment)
Launch price. 12, 24 and 52-week plans cost $927, $1,734 and $3,497 ($309, $289 and $269 per 4-week shipment)
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What’s included
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Ounce
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Not disclosed
Lab work
Included
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
Ounce
6.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Amazon One Medical | Ounce |
|---|---|---|
| Starting Price | ✓$149/mo | $249/mo |
| Features | 6 features | 6 features |
| States Available | 50 | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →About Ounce
Ounce is a new telehealth weight-loss brand that has not opened yet: for now you take a two-minute eligibility check and hold a spot with a refundable $25 deposit. It plans to offer compounded semaglutide and tirzepatide injections and a semaglutide dissolving tablet. Month-to-month prices are $249 for semaglutide, $279 for the tablet and $339 for tirzepatide, with clinician visits and baseline labs included.
Read our full Ounce review →Pros & Cons
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Ounce
What we like
- Every plan price is posted on the home page and again on the result screen before you give any contact details
- The monthly price includes clinician visits, messaging and baseline labs at Quest or Labcorp
- Offers compounded semaglutide and tirzepatide injections plus a semaglutide dissolving tablet for people who avoid needles
- The eligibility check takes about two minutes and needs no account or payment to see your result
- The $25 deposit is fully refundable and counts toward your first month if you start treatment
- The site says you can cancel any time and request a refund for any month whose medication has not been ordered
Watch-outs
- Ounce has not launched yet, so you can only reserve a spot and wait for an email saying it has opened in your state
- Neither the medical practice that would treat you nor the dispensing pharmacy is named anywhere on the site
- Longer plans are priced per month but billed per 4-week shipment, so a 52-week plan bills 13 shipments, not 12
- The home page says review usually happens without a video call, but another page describes a video visit first
- The brand is days old, with no LegitScript record and no independent customer reviews
- Shipping costs are not stated, and the coaching program is an optional extra
Our Verdict
Amazon One Medical edges out Ounce with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. Ounce remains a solid alternative, especially if you're looking for people who want to lock in a posted all-in GLP-1 price with labs included before the service opens.
Choose Amazon One Medical if…
You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.
Choose Ounce if…
You want people who want to lock in a posted all-in GLP-1 price with labs included before the service opens and a starting price around $249/mo.
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Maximus
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From $199.99/mo
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LegitScript-certified compounded GLP-1 via named pharmacies
From $149/mo
Get started →Enhance MD
Lab-monitored compounded GLP-1 with mandatory video visit
From $112/mo
Get started →Amazon One Medical vs Ounce: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.