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Amazon One Medical vs NuDay Rx

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Amazon One Medical logo

Amazon One Medical

8.5
★★★★4.3/5

Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery

Visit Amazon One Medical
VS
NuDay Rx logo

NuDay Rx

7.3
★★★3.7/5

Best for: both compounded and brand GLP-1 options with coaching and a doctor consult

Visit NuDay Rx

Amazon One Medical and NuDay Rx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $249/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

NuDay Rx

MonthlyCompounded
$249/mo
semaglutide

'Compounded Semaglutide $249.00'. Oral semaglutide tablets are the same $249.

MonthlyCompounded
$329/mo
tirzepatide

'Personalized Tirzepatide Compound $329.00'. The tablet form is dearer at $399.

Personalized tirzepatide tabletsCompounded
$399/mo
tirzepatide

'Personalized Tirzepatide Tablets $399.00' — $70 above the injectable compound, which is the reverse of most sellers here.

Wegovy® — brandCompounded
$990/mo
semaglutide

'Wegovy® $990.00'. NuDay also lists Ozempic® $705, Rybelsus® $645 and Mounjaro® $835.

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What’s included

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

NuDay Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Amazon One Medical

8.5/10

Overall

NuDay Rx

7.3/10

Value25%

8.5A
vs
B
7.0

Effectiveness25%

8.5A
vs
B
8.0

User Experience15%

8.0A
vs
B
7.0

Trust & Safety15%

8.8A
vs
B
6.8

Accessibility10%

9.5A
vs
B
7.0

Support10%

8.0A
vs
B
7.9

Features & Coverage

FeatureAmazon One MedicalNuDay Rx
Starting Price$149/mo$249/mo
Features6 features8 features
States Available50Not disclosed
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

About NuDay Rx

NuDay Rx is a GLP-1 weight-loss telehealth service (on the CareValidate/careGLP platform) that pairs medication with video coaching and lifestyle support. It offers a wide menu: compounded semaglutide ($249) and tirzepatide ($329), oral semaglutide/tirzepatide tablets, a 'GLP-Squared' combo, plus brand-name Ozempic, Wegovy, Mounjaro, and Rybelsus at cash prices. After an online intake and licensed-doctor consult, the prescription is delivered to your door. A full legal suite is published; the compounding pharmacy is not named and no LegitScript certification is shown.

Read our full NuDay Rx review →

Pros & Cons

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

NuDay Rx

What we like

  • Wide selection — compounded semaglutide ($249) and tirzepatide ($329), oral tablet options, plus brand GLP-1 (cash pay)
  • Includes video coaching and lifestyle support with a licensed-doctor consult
  • Full legal suite published (Terms, Privacy, Privacy Practices, Medical Consent)
  • Prescription delivered to your door after an online intake and consult

Watch-outs

  • Compounded semaglutide ($249) is pricier than some budget competitors
  • Compounding pharmacy partner not named
  • Not LegitScript-certified (no certification displayed)
  • Runs on a shared white-label telehealth platform (CareValidate/careGLP)

Our Verdict

Winner: Amazon One Medical

Amazon One Medical edges out NuDay Rx with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. NuDay Rx remains a solid alternative, especially if you're looking for both compounded and brand GLP-1 options with coaching and a doctor consult.

Choose Amazon One Medical if…

You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.

Choose NuDay Rx if…

You want both compounded and brand GLP-1 options with coaching and a doctor consult and a starting price around $249/mo.

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Amazon One Medical vs NuDay Rx: FAQ

Amazon One Medical is cheaper. Its lowest ongoing monthly cash price is $149/mo, compared with $249/mo for NuDay Rx. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Amazon One Medical scores higher overall at 8.5/10 versus 7.3/10, and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. That said, NuDay Rx is a better fit if you want both compounded and brand GLP-1 options with coaching and a doctor consult.
Amazon One Medical lists availability in 50 states, while NuDay Rx's state list is not publicly listed.
Neither Amazon One Medical nor NuDay Rx is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.

Key terms, explained

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Continue exploring Amazon One Medical and NuDay Rx head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.