Amazon One Medical vs Nolu
An in-depth comparison of two leading GLP-1 Providers
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Amazon One Medical
Best for: the most authoritative brand-name GLP-1 channel, with same-day delivery
Visit Amazon One Medical →
Nolu
Best for: Flat-rate GLP-1 with both oral and injectable options, named pharmacy partners
Visit Nolu →Amazon One Medical and Nolu are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $249/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.2 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Amazon One Medical
Nolu
Priced and labeled "per 4 weeks" on Nolu's own pricing page, not per calendar month
Priced and labeled "per 4 weeks" on Nolu's own pricing page, not per calendar month
Separate oral-tablet plan from the injectable semaglutide row above
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What’s included
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Nolu
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
Nolu
7.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Amazon One Medical | Nolu |
|---|---|---|
| Starting Price | ✓$149/mo | $249/mo |
| Features | 6 features | ✓8 features |
| States Available | 50 | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →About Nolu
Nolu (Nolu LLC) is a direct-to-consumer telehealth platform offering compounded GLP-1 weight-loss treatment after an online medical intake reviewed by a licensed clinician. It sells injectable semaglutide, injectable tirzepatide, and a once-daily oral semaglutide tablet, each billed at a flat rate "every 4 weeks" regardless of dose. Plans start at $249 per 4 weeks for semaglutide and include the consultation, medication, and shipping; the company names four contracted pharmacy partners and says it currently serves all 50 states plus Washington D.C.
Read our full Nolu review →Pros & Cons
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Nolu
What we like
- Price includes consultation, medication, and shipping — no separate fees for the plan you pick
- Flat pricing — "same price at every dose" as you titrate up
- Names four contracted pharmacy partners in its Terms of Service
- Prices ($249-$339 per 4 weeks) are shown before you start the intake quiz
- Oral (daily tablet) and injectable semaglutide both offered, plus tirzepatide
- No long-term contract; cancel anytime with 72 hours' notice
- FSA/HSA eligible and free expedited shipping on every order
Watch-outs
- Billed "every 4 weeks," not monthly — 13 charges a year, though the site does disclose this upfront
- No LegitScript or PCAB certification found for the company or its named pharmacies
- No Trustpilot, Google, or BBB rating displayed to independently verify service quality
- Intake asks for your name, phone, and email before any health questions
- State availability is a blanket "all 50 states + DC" claim with no verifiable per-state list
- Monthly-billed plans get no refund for the cancellation month or any prior month
- Does not accept insurance — cash-pay only
Our Verdict
Amazon One Medical edges out Nolu with a higher overall score of 8.5/10 and is particularly strong for the most authoritative brand-name GLP-1 channel, with same-day delivery. Nolu remains a solid alternative, especially if you're looking for Flat-rate GLP-1 with both oral and injectable options, named pharmacy partners.
Choose Amazon One Medical if…
You want the most authoritative brand-name GLP-1 channel, with same-day delivery and a starting price around $149/mo.
Choose Nolu if…
You want Flat-rate GLP-1 with both oral and injectable options, named pharmacy partners and a starting price around $249/mo.
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Direct Meds
Listed for disclosure only — see its FDA warning and BBB complaints first
From $249/mo
Get started →Maximus
Men seeking compounded GLP-1 alongside testosterone optimization
From $199.99/mo
Get started →Sesame Care
Brand-name GLP-1s at cash prices, no compounding
From $25/mo
Get started →Amazon One Medical vs Nolu: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.