Amazon One Medical vs Liberty
An in-depth comparison of two leading GLP-1 Providers
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Amazon One Medical
Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings
Visit Amazon One Medical →
Liberty
Best for: people who want nationwide compounded semaglutide or tirzepatide from 503B-sourced pharmacies
Visit Liberty →Amazon One Medical and Liberty are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $199/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Amazon One Medical
Liberty
Compounded semaglutide weekly injection, flat $199/mo; drops to about $171/mo on a 3-month supply. Sourced from a 503B outsourcing facility; Rx after clinician review.
Compounded tirzepatide (dual GIP/GLP-1) weekly injection, flat $299/mo. Sourced from a 503B outsourcing facility; Rx after clinician review.
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What’s included
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Liberty
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
Liberty
7.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Amazon One Medical | Liberty |
|---|---|---|
| Starting Price | ✓$149/mo | $199/mo |
| Features | 6 features | ✓8 features |
| States Available | 50 | Not disclosed |
| Compounded | — | — |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →About Liberty
Liberty (Liberty Health) is a nationwide online weight-loss and wellness service offering compounded GLP-1 sourced from FDA-registered 503B outsourcing facilities. After a quiz and licensed-provider review, it prescribes compounded semaglutide injection at $199/month (about $171/month on a 3-month supply) and compounded tirzepatide injection at $299/month, marketed as up to 85% less than brand-name. It serves all 50 states with free shipping, 24/7 support, and FSA/HSA acceptance, and also offers microdosing, NAD+, sermorelin, and metformin. It does not name its specific pharmacy partner.
Read our full Liberty review →Pros & Cons
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Liberty
What we like
- Compounded GLP-1 sourced from FDA-registered 503B outsourcing facilities, a stricter standard than the 503A pharmacies many competitors use
- Transparent flat pricing: compounded semaglutide $199/mo (about $171/mo on a 3-month supply) and tirzepatide $299/mo
- Nationwide in all 50 states with free discreet shipping, 24/7 support, and FSA/HSA acceptance
- Multi-vertical menu beyond weight loss (low-dose microdosing, NAD+, sermorelin, metformin) for patients who want bundled wellness care
Watch-outs
- Does not name its specific compounding pharmacy partner, only that it is a 503B facility
- Tirzepatide at $299/mo is mid-market rather than the cheapest option among compounded providers
- Generic corporate branding (Liberty Health) with limited public detail on the operating entity
- Compounded medication only — no brand-name or insurance-covered GLP-1 path
Our Verdict
Amazon One Medical edges out Liberty with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. Liberty remains a solid alternative, especially if you're looking for people who want nationwide compounded semaglutide or tirzepatide from 503B-sourced pharmacies.
Choose Amazon One Medical if…
You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.
Choose Liberty if…
You want people who want nationwide compounded semaglutide or tirzepatide from 503B-sourced pharmacies and a starting price around $199/mo.
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Get started →Amazon One Medical vs Liberty: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.